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http://dx.doi.org/10.13104/jksmrm.2014.18.1.59

SAPHO Syndrome in a Patient with Breast Cancer Mimicking Bone Metastasis: A Case Report  

Ko, Kyungran (Department of Radiology, Center for Breast Cancer, National Cancer Center of Korea)
Suh, Hee Jung (Department of Radiology, Center for Cancer Prevention and Early Detection, National Cancer Center of Korea)
You, Ji Young (Department of Surgery, Center for Breast Cancer, National Cancer Center of Korea)
Jung, So-Youn (Department of Surgery, Center for Breast Cancer, National Cancer Center of Korea)
Kwon, Youngmee (Department of Pathology, Center for Breast Cancer, National Cancer Center of Korea)
Koh, Young Whan (Department of Radiology, Center for Liver Cancer, National Cancer Center of Korea)
Publication Information
Investigative Magnetic Resonance Imaging / v.18, no.1, 2014 , pp. 59-63 More about this Journal
Abstract
A 66-year-old woman was transferred to our hospital due to her right breast cancer. Preoperative breast MRI shows 1.9 cm malignancy on her right breast (cT1N0M0) and incidentally found osteosclerotic change of left coststernoclavicular region. Bone scintigraphy showed hot uptake and the possibility of bone metastasis was not excluded. However, because the bone metastasis is not common in early stage cancer and the costosternoclavicular region is not common site, other possibility should be considered. SAPHO syndrome can be diagnosed even in the absence of dermatosis when there is an axial or appendicular osteitis and hyperostosis, especially in costosternoclavicular region. Though breast imaging specialists are not accustomed to this disease entity, awareness and diagnosis of the SAPHO syndrome can help differentiate bone metastasis.
Keywords
Breast cancer; SAPHO syndrome; Costosternoclavicular region;
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