Browse > Article
http://dx.doi.org/10.13104/jksmrm.2013.17.3.192

Dynamic Contrast-Enhanced MR Imaging in Detecting Local Tumor Progression after HIFU Ablation of Localized Prostate Cancer  

Park, Jung Jae (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Kim, Chan Kyo (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Lee, Hyun Moo (Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Park, Byung Kwan (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Park, Sung Yoon (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Publication Information
Investigative Magnetic Resonance Imaging / v.17, no.3, 2013 , pp. 192-199 More about this Journal
Abstract
Purpose : To retrospectively evaluate the diagnostic performance of dynamic contrast-enhanced MR imaging (DCE-MRI) in detecting recurrent prostate cancer after HIFU of clinically localized cancer, as compared with T2-weighted imaging (T2WI). Materials and Methods: Twenty-six patients with increased prostate-specific antigen levels after HIFU were included in this study. All MR examinations were performed using T2WI and DCE-MRI, followed by transrectal ultrasound-guided biopsy. MRI and biopsy results were correlated in six prostate sectors. Residual or recurrent cancer after HIFU was defined as local tumor progression if biopsy results showed any cancer foci. Two independent readers interpreted the MR images. Results: Of 156 prostate sectors, 51 (33%) were positive for cancer in 17 patients. For detecting local tumor progression, the sensitivity of DCE-MRI and T2WI was 80% and 57% for reader 1 (P < 0.001) versus 84% and 61% for reader 2 (P < 0.001), respectively. The specificity and overall accuracy between DCE-MRI and T2WI showed no statistical difference in both readers (P > 0.05). Interobserver agreement of DCE-MRI and T2WI was moderate and fair, respectively. Conclusion: For detecting local tumor progression of prostate cancer after HIFU, DCE-MRI was more sensitive than T2WI, with less interobserver variability.
Keywords
High intensity focused ultrasound; Localized prostate cancer; Magnetic resonance imaging (MRI) Dynamic contrast-enhanced MRI;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Ocak I, Bernardo M, Metzger G, et al. Dynamic contrastenhanced MRI of prostate cancer at 3 T: a study of pharmacokinetic parameters. AJR Am J Roentgenol 2007;189:849
2 Aus G, Abbou CC, Bolla M, et al. EAU guidelines on prostate cancer. Eur Urol 2005;48:546-551   DOI   ScienceOn
3 Aus G. Current status of HIFU and cryotherapy in prostate cancer--a review. Eur Urol 2006;50:927-934; discussion 934   DOI   ScienceOn
4 Poissonnier L, Chapelon JY, Rouviere O, et al. Control of prostate cancer by transrectal HIFU in 227 patients. Eur Urol 2007;51:381-387   DOI   ScienceOn
5 Forsythe K, Blacksburg S, Stone N, Stock RG. Intensitymodulated radiotherapy causes fewer side effects than threedimensional conformal radiotherapy when used in combination with brachytherapy for the treatment of prostate cancer. Int J Radiat Oncol Biol Phys 2012;83:630-635   DOI   ScienceOn
6 Orsi F, Arnone P, Chen W, Zhang L. High intensity focused ultrasound ablation: a new therapeutic option for solid tumors. J Cancer Res Ther 2010;6:414-420   DOI   ScienceOn
7 Colombel M, Gelet A. Principles and results of high-intensity focused ultrasound for localized prostate cancer. Prostate Cancer Prostatic Dis 2004;7:289-294   DOI   ScienceOn
8 Rebillard X, Gelet A, Davin JL, et al. Transrectal high-intensity focused ultrasound in the treatment of localized prostate cancer. J Endourol 2005;19:693-701   DOI   ScienceOn
9 Rouviere O, Lyonnet D, Raudrant A, et al. MRI appearance of prostate following transrectal HIFU ablation of localized cancer. Eur Urol 2001;40:265-274   DOI   ScienceOn
10 Kirkham AP, Emberton M, Hoh IM, Illing RO, Freeman AA, Allen C. MR imaging of prostate after treatment with highintensity focused ultrasound. Radiology 2008;246:833-844   DOI   ScienceOn
11 Kim CK, Park BK, Lee HM, Kim SS, Kim E. MRI techniques for prediction of local tumor progression after high-intensity focused ultrasonic ablation of prostate cancer. AJR Am J Roentgenol 2008;190:1180-1186   DOI   ScienceOn
12 Ben Cheikh A, Girouin N, Ryon-Taponnier P, et al. MR detection of local prostate cancer recurrence after transrectal highintensity focused US treatment: preliminary results. J Radiol 2008;89:571-577   DOI
13 Punwani S, Emberton M, Walkden M, et al. Prostatic cancer surveillance following whole-gland high-intensity focused ultrasound: comparison of MRI and prostate-specific antigen for detection of residual or recurrent disease. Br J Radiol 2012;85:720-728   DOI   ScienceOn
14 Goldberg SN, Grassi CJ, Cardella JF, et al. Image-guided tumor ablation: standardization of terminology and reporting criteria. Radiology 2005;235:728-739   DOI   ScienceOn
15 Engelbrecht MR, Huisman HJ, Laheij RJ, et al. Discrimination of prostate cancer from normal peripheral zone and central gland tissue by using dynamic contrast-enhanced MR imaging. Radiology 2003;229:248-254   DOI   ScienceOn
16 Futterer JJ, Engelbrecht MR, Huisman HJ, et al. Staging prostate cancer with dynamic contrast-enhanced endorectal MR imaging prior to radical prostatectomy: experienced versus less experienced readers. Radiology 2005;237:541-549   DOI   ScienceOn
17 Isebaert S, Van den Bergh L, Haustermans K, et al. Multiparametric MRI for prostate cancer localization in correlation to whole-mount histopathology. J Magn Reson Imaging 2012
18 Kim JK, Hong SS, Choi YJ, et al. Wash-in rate on the basis of dynamic contrast-enhanced MRI: usefulness for prostate cancer detection and localization. J Magn Reson Imaging 2005;22:639-646   DOI   ScienceOn
19 Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977;33:159-174   DOI   ScienceOn
20 Donahue KM, Weisskoff RM, Parmelee DJ, et al. Dynamic Gd- DTPA enhanced MRI measurement of tissue cell volume fraction. Magn Reson Med 1995;34:423-432   DOI
21 Gelet A, Chapelon JY, Poissonnier L, et al. Local recurrence of prostate cancer after external beam radiotherapy: early experience of salvage therapy using high-intensity focused ultrasonography. Urology 2004;63:625-629   DOI   ScienceOn