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Ancient Schwannoma of the Thigh mimicking a Plexiform Malignant Peripheral Nerve Sheath Tumor: A Case Report  

Lee, Yeon-Soo (Department of Radiology, Daejeon St. Mary's Hospital, The Catholic University of Korea)
Park, Sang-Eun (Department of Orthopedic Surgery, Daejeon St. Mary's Hospital, The Catholic University of Korea)
Lee, Jung-Uee (Department of Pathology, Daejeon St. Mary's Hospital, The Catholic University of Korea)
Publication Information
Investigative Magnetic Resonance Imaging / v.15, no.2, 2011 , pp. 170-175 More about this Journal
Abstract
Ancient schwannoma is a rare variant of schwannoma and a slow growing benign tumor associated with degeneration that may be diagnosed as a malignant tumor, because it presents with a large size and an inhomogeneous signal intensity. The main differential diagnosis of plexiform soft tissue tumor includes plexiform neurofibroma, malignant peripheral nerve sheath tumor (MPNST). In this case, we describe the MRI findings in a case of ancient schwannoma involving left thigh of a 63-year-old woman mimicking a plexiform MPNST. The tumor appeared as an inhomogeneous signal intensity and multinodular appearance, causing misdiagnosis as a plexiform MPNST.
Keywords
Schwannoma; Plexiform; Thigh; Magnetic resonance (MR);
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1 Enzinger FM, Weiss SW. Benign tumors of peripheral nerves. Soft tissue tumors. 3rd ed. St Louis: Mosby, 1995:821-888
2 Dahl I. Ancient neurilemoma (schwannoma). Acta Pathol Microbiol Scand Sect A 1977;85:812-818
3 Klijanienko J, Caillaud JM, Lagace R. Cytohistologic correlations in schwannomas (neurilemmomas), including "ancient," cellular, and epithelioid variants. Diagn Cytopathol 2006;34:517-522   DOI   ScienceOn
4 Hebert-Blouin MN, Amrami KK, Scheithauer BW, Spinner RJ. Multinodular/plexiform (multifascicular) schwannomas of major peripheral nerves: an underrecognized part of the spectrum of schwannomas. J Neurosurg 2010;112:372-382   DOI   ScienceOn
5 Woertler K. Tumors and tumor-like lesions of peripheral nerves. Semin Musculoskelet Radiol 2010;14:547-558   DOI   ScienceOn
6 Isobe K, Shimizu T, Akahane T, Kato H. Imaging of ancient schwannoma. AJR Am J Roentgenol 2004;183:331-336
7 Lee YS, Kim JO, Park SE. Ancient schwannoma of the thigh mimicking a malignant tumour: a report of two cases, with emphasis on MRI findings. Br J Radiol 2010;83:e154-157   DOI   ScienceOn
8 Agaram NP, Prakash S, Antonescu CR. Deep-seated plexiform schwannoma: a pathologic study of 16 cases and comparative analysis with the superficial variety. Am J Surg Pathol 2005;29:1042-1048
9 구희연, 이명준, 이창준, 유정현. 드문부위에 발생한 신경초종: 2예 보고. 대한방사선의학회지 2001;45:571-574
10 Kransdorf MJ, Murphey MD. Neurogenic tumors. Imaging of soft tissue tumors. 2nd ed. Philadelphia: Lippncott Williams & Wilkins; 2006:328-380