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Sino-orbital Granulocytic Sarcoma Causing Bilateral Proptosis As an Initial Manifestation of Acute Myelogenous Leukemia (AML): A Case Report  

Kim, Hee-Sun (Department of Radiology, Ansan Hospital, College of Medicine, Korea University)
Je, Bo-Kyung (Department of Radiology, Ansan Hospital, College of Medicine, Korea University)
Lee, Young-Hen (Department of Radiology, Ansan Hospital, College of Medicine, Korea University)
Kim, Baek-Hyun (Department of Radiology, Ansan Hospital, College of Medicine, Korea University)
Publication Information
Investigative Magnetic Resonance Imaging / v.14, no.1, 2010 , pp. 74-77 More about this Journal
Abstract
Granulocytic sarcoma is a manifestation of myelogenous leukemia, which means a solid mass consisting of primitive precursors of the granulocytic series of white blood cells. We present CT and MR imaging findings of bilateral sino-orbital granulocytic sarcoma in a 22-month-old boy. The mass involved bilateral orbital fossa which resulted in bilateral proptosis. Moreover, the mass extended to the almost skull base including paranasal sinuses, maxilla, temporal bone, zygomatic bone, sphenoid bone, ethmoid, and palatine bone. The adjacent dura was continuously thickened and the lower half of cavernous sinus was also involved. The patient was diagnosed as AML (M5) with t(8,21) translocation through a chromosome study from the bone marrow.
Keywords
Leukemia; Myeloid; Acute; Granulocytic sarcoma; Orbital neoplasms;
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1 Binder C, Tiemann M, Haase D, Humpe A, Kneba M. Isolated meningeal chloroma (granulocytic sarcoma) - a case report and review of the literature. Ann Hematol 2000;79(8):459-462   DOI   ScienceOn
2 Chung EM, Murphey MD, Specht CS, Cube R, Smirniotopoulos JG. From the Archives of the AFIP. Pediatric orbit tumors and tumorlike lesions: osseous lesions of the orbit. Radiographics 2008;28(4):1193-1214   DOI   ScienceOn
3 Guermazi A, Feger C, Rousselot P, et al. Granulocytic sarcoma (chloroma): imaging findings in adults and children. AJR Am J Roentgenol 2002;178(2):319-325   DOI
4 Uyesugi WY, Watabe J, Petermann G. Orbital and facial granulocytic sarcoma (chloroma): a case report. Pediatr Radiol 2000;30(4):276-278   DOI   ScienceOn
5 Bulas RB, Laine FJ, Das Narla L. Bilateral orbital granulocytic sarcoma (chloroma) preceding the blast phase of acute myelogenous leukemia: CT findings. Pediatr Radiol 1995;25(6):488- 489   DOI   ScienceOn
6 Pui MH, Fletcher BD, Langston JW. Granulocytic sarcoma in childhood leukemia: imaging features. Radiology 1994;190(3): 698-702   DOI
7 Pui CH. Childhood leukaemias. Cambridge: cambridge university press. 1999:288-312 443-481
8 Jakobiec FA. Granulocytic sarcoma. AJNR Am J Neuroradiol 1991;12(2):263-264
9 Stein-Wexler R, Wootton-Gorges SL, West DC. Orbital granulocytic sarcoma: an unusual presentation of acute myelocytic leukemia. Pediatr Radiol 2003;33(2):136-139   DOI