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Cortical Thickness Estimation Using DIR Imaging with GRAPPA Factor 2  

Choi, Na-Rae (School of Electrical and Electronic Engineering, Yonsei University)
Nam, Yoon-Ho (School of Electrical and Electronic Engineering, Yonsei University)
Kim, Dong-Hyun (School of Electrical and Electronic Engineering, Yonsei University)
Publication Information
Investigative Magnetic Resonance Imaging / v.14, no.1, 2010 , pp. 56-63 More about this Journal
Abstract
Purpose : DIR image is relatively free from susceptibility artifacts therefore, DIR image can make it possible to reliably measure cortical thickness/volume. One drawback of the DIR acquisition is the long scan time to acquire the fully sampled 3D data set. To solve this problem, we applied a parallel imaging method (GRAPPA) and verify the reliability of using the volumetric study. Materials and methods : Six healthy volunteers (3 males and 3 females; age $25.33{\pm}2.25$ years) underwent MRI using the 3D DIR sequence at a 3.0T Siemens Tim Trio MRI scanner. GRAPPA simulation was performed from the fully sampled data set for reduction factor 2. Data reconstruction was performed using MATLAB R2009b. Freesurfer v.4.3.0 was used to evaluate the cortical thickness of the entire brain, and to extract white matter information from the DIR image, Analyze 9.0 was used. The global cortical thickness estimated from the reconstructed image was compared with reference image by using a T-test in SPSS. Results : Although reduced SNR and blurring are observed from the reconstructed image, in terms of segmentation the effect was not so significant. The volumetric result was validated that there were no significant differences in many cortical regions. Conclusion : This study was performed with DIR image for a volumetric MRI study. To solve the long scan time of 3D DIR imaging, we applied GRAPPA algorithm. According to the results, fast imaging can be done with reduction factor 2 with little loss of image quality at 3.0T.
Keywords
DIR imaging; GRAPPA; Cortical thickness estimation; Volumetry;
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1 Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P. SENSE: sensitivity encoding for fast MRI. Magn Reson Med 1999;42(5):952-962   DOI   ScienceOn
2 Han X, Jovicich J, Salat D, van der Kouwe A, Quinn B, Czanner S, Busa E, Pacheco J, Albert M, Killiany R, Maguire P, Rosas D, Makris N, Dale A, Dickerson B, Fischl B. Reliability of MRI-derived measurements of human cerebral cortical thickness: the effects of field strength, scanner upgrade and manufacturer. Neuroimage 2006;32(1):180-194   DOI   ScienceOn
3 Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage 1999;9(2):179-194   DOI   ScienceOn
4 Fischl B, Dale AM. Measuring the thickness of the human cerebral cortex from magnetic resonance images. P Natl Acad Sci USA 2000;97(20):11050-11055   DOI
5 Lee H, Kim EY, Seo JS, Park J. Reliable Cortical Thickness Estimation With Reduction of Susceptibility-Induced Signal Loss Using Optimized T1-weighted Single Slab Turbo Spin Echo Pulse Sequence. 2010; 18th Scientific Meeting of the International Society of Magnetic Resonance in Medicine, Stockholm, Sweden. p 686
6 Park MH, Lee JW, Lee KW, Ryu CW, Jahng GH. Optimizations of 3D MRI Techniques in Brain by Evaluating SENSE Factors. J Korean Soc Magn Reson Med 2009;13:161- 170   과학기술학회마을
7 Huang F, Li Y, Vijayakumar S, Hertel S, Duensing GR. Highpass GRAPPA: An image support reduction technique for improved partially parallel imaging. Magnetic Resonance in Medicine 2008;59(3):642-649   DOI   ScienceOn
8 Sodickson DK, Manning WJ. Simultaneous acquisition of spatial harmonics (SMASH): fast imaging with radiofrequency coil arrays. Magn Reson Med 1997;38(4):591-603   DOI   ScienceOn
9 Park HJ, Youn T, Jeong SO, Oh MK, Kim SY, Kim EY. SENSE factors for reliable cortical thickness measurement. Neuroimage 2008;40(1):187-196   DOI   ScienceOn
10 Lindholm TL, Botes L, Engman EL, Frank A, Jonsson T, Svensson L, Julin P. Parallel imaging: is GRAPPA a useful acquisition tool for MR imaging intended for volumetric brain analysis? BMC Med Imaging 2009;9:15   DOI
11 Yoo E, Kim D-H, Park H-J, Kim E-Y. Unreliability of Cortical Volumetry in Regions near The Skull Base on 3D T1-weighted Imaging: Comparision study with 3D Double Inversion-recovery Imaging. 2008; 16th Scientific Meeting of the International Society of Magnetic Resonance in Medicine, Toronto, Canada. p 3502
12 Mugler JP, 3rd, Brookeman JR. Rapid three-dimensional T1- weighted MR imaging with the MP-RAGE sequence. J Magn Reson Imaging 1991;1(5):561-567   DOI   ScienceOn
13 Edelman RR, Chien D, Kim D. Fast selective black blood MR imaging. Radiology 1991;181(3):655-660   DOI
14 Griswold MA, Jakob PM, Heidemann RM, Nittka M, Jellus V, Wang J, Kiefer B, Haase A. Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med 2002;47(6):1202-1210   DOI   ScienceOn
15 Pouwels PJ, Kuijer JP, Mugler JP, 3rd, Guttmann CR, Barkhof F. Human gray matter: feasibility of single-slab 3D double inversion- recovery high-spatial-resolution MR imaging. Radiology 2006;241(3):873-879   DOI   ScienceOn