Evaluation of Newly Isolated Klebsiella pneumoniae Strains for the Co-Production of 3-hydroxypropionic acid and 1,3-propanediol from Glycerol
![]() |
Ko, Yeounjoo
(Department of Chemical and Biomolecular Engineering, Pusan National University)
Seol, Eunhee (Department of Chemical and Biomolecular Engineering, Pusan National University) Sekar, Balaji Sundara (Department of Chemical and Biomolecular Engineering, Pusan National University) Kwon, Seongjin (Department of Chemical and Biomolecular Engineering, Pusan National University) Lee, Jaehyeon (Department of Chemical and Biomolecular Engineering, Pusan National University) Park, Sunghoon (Department of Chemical and Biomolecular Engineering, Pusan National University) |
1 | Future chemical industry, Cover story (Catalyst). http://www.cischem.com/chemical_report/chem_re_content.asp?data_part1=chem_rep&docnum=cr_99/cr99cover.asp (2016). |
2 | Bozell, J. J. and G. R. Petersen (2010) Technology development for the production of biobased products from biorefinery carbohydrates - the US Department of Energy's "top 10" revisited. Green Chem. 12: 539-554. DOI |
3 | Kumar, V., S. Ashok, and S. Park (2013) Recent advances in biological production of 3-hydroxypropionic acid. Biotechnol. Adv. 31: 945-961. DOI |
4 | Raj, S. M., C. Rathnasingh, J. E. Jo, and S. Park (2008) Production of 3-hydroxypropionic acid from glycerol by a novel recombinant Escherichia coli BL21 strain. Process Biochem. 43: 1440-1446. DOI |
5 | Rathnasingh, C., S. M. Raj, J. E. Jo, and S. Park (2009) Development and evaluation of efficient recombinant Escherichia coli strains for the production of 3-hydroxypropionic acid from glycerol. Biotechnol. Bioeng. 104: 729-739. |
6 | Raj, S. M., C. Rathnasingh, W. C. Jung, and S. Park (2009) Effect of process parameters on 3-hydroxypropionic acid production from glycerol using a recombinant Escherichia coli. Appl. Microbiol. Biotechnol. 84: 649-657. DOI |
7 | Ko, Y., S. Ashok, S. Zhou, V. Kumar, and S. Park (2012) Aldehyde dehydrogenase activity is important to the production of 3-hydroxypropionic acid from glycerol by recombinant Klebsiella pneumoniae. Process Biochem. 47: 1135-1143. DOI |
8 |
Ashok, S., S.M. Raj, Y. Ko, M. Sankaranarayanan, S. Zhou, V. Kumar, and S. Park (2013) Effect of puuC overexpression and nitrate addition on glycerol metabolism and anaerobic 3-hydroxypropionic acid production in recombinant Klebsiella pneumoniae |
9 |
Ashok, S., M. Sankaranarayanan, Y. Ko, K. E. Jae, S. K. Ainala, V. Kumar, and S. Park (2013) Production of 3-hydroxypropionic acid from glycerol by recombinant Klebsiella pneumoniae |
10 | Zhou, S., C. Catherine, C. Rathnasingh, A. Somasundar, and S. Park (2013) Production of 3-hydroxypropionic acid from glycerol by recombinant Pseudomonas denitrificans. Biotechnol. Bioeng. 110: 3177-3187. DOI |
11 | Maervoet, V. E., M. De Mey, J. Beauprez, S. De Maeseneire, and W. K. Soetaert (2010) Enhancing the microbial conversion of glycerol to 1,3-propanediol using metabolic engineering. Org. Process Res. Dev. 15: 189-202. |
12 | Kumar, V., M. Durgapal, M. Sankaranarayanan, A. Somasundar, C. Rathnasingh, H. Song, D. Seung, and S. Park (2016) Effects of mutation of 2, 3-butanediol formation pathway on glycerol metabolism and 1, 3-propanediol production by Klebsiella pneumoniae J2B. Bioresour. Technol. 214: 432-440. DOI |
13 | Kumar, V., M. Sankaranarayanan, M. Durgapal, S. Zhou, Y. Ko, S. Ashok, R. Sarkar and S. Park (2013) Simultaneous production of 3-hydroxypropionic acid and 1, 3-propanediol from glycerol using resting cells of the lactate dehydrogenase-deficient recombinant Klebsiella pneumoniae overexpressing an aldehyde dehydrogenase. Bioresour. Technol. 135: 555-563. DOI |
14 | Durgapal, M., V. Kumar, T. H. Yang, H. J. Lee, D. Seung, and S. Park. (2014) Production of 1, 3-propanediol from glycerol using the newly isolated Klebsiella pneumoniae J2B. Bioresour. Technol. 159: 223-231. DOI |
15 | Ashok, S., S. M. Raj, C. Rathnasingh, and S. Park (2011) Development of recombinant Klebsiella pneumoniae ΔdhaT strain for the co-production of 3-hydroxypropionic acid and 1,3-propanediol from glycerol. Appl. Microbiol. Biotechnol. 90: 1253-1265. DOI |
16 | Kumar, V., M. Sankaranarayanan, K. E. Jae, M. Durgapal, S. Ashok, Y. Ko, R. Sarkar, and S. Park (2012) Co-production of 3-hydroxypropionic acid and 1, 3-propanediol from glycerol using resting cells of recombinant Klebsiella pneumoniae J2B strain overexpressing aldehyde dehydrogenase. Appl. Microbiol. Biotechnol. 96: 373-383. DOI |
17 | Huang, Y., Z. Li, K. Shimizu, and Q. Ye (2012) Simultaneous production of 3-hydroxypropionic acid and 1,3-propanediol from glycerol by a recombinant strain of Klebsiella pneumoniae. Bioresour. Technol. 103: 351-359. DOI |
18 | Huang, Y., Z. Li, K. Shimizu, and Q. Ye (2013) Co-production of 3-hydroxypropionic acid and 1,3-propanediol by Klebseilla pneumoniae expressing aldH under microaerobic conditions. Bioresour. Technol. 128: 505-512. DOI |
19 | Lama, S., S. M. Ro, E. Seol, B. S. Sekar, S. K. Ainala, J. Thangappan, H. Song, and S. Park (2015) Characterization of 1,3-propanediol oxidoreductase (DhaT) from Klebsiella pneumoniae J2B. Biotechnol. Bioprocess Eng. 20: 971-979. DOI |
20 | Arasu, M. V., V. Kumar, S. Ashok, H. Song, C. Rathnasingh, H. J. Lee, D. Seung, and S. Park (2011) Isolation and characterization of the new Klebsiella pneumoniae J2B strain showing improved growth characteristics with reduced lipopolysaccharide formation. Biotechnol. Bioprocess Eng. 16: 1134-1143. DOI |
21 | Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254. DOI |
22 | Chmielowski, R. A., H. S. Wu, and S. S. Wang (2007) Scale-up of upstream and downstream operations for the production of glucosamine using microbial fermentation. Biotechnol. J. 2: 996-1006. DOI |
23 | Jiang, W., S. Wang, Y. Wang, and B. Fang (2016) Key enzymes catalyzing glycerol to 1, 3-propanediol. Biotechnol. Biofuels. 9: 1. DOI |
![]() |