Study on the Anti-inflammatory Effect and Mechanism of Prunus mume Extract Regarding NF-κB
![]() |
Seo, Won-Sang
(Department of Microbial Engineering, Konkuk university)
Oh, Han-Na (Charmzone R&D Center, Charmzone Cosmetic, Ltd.) Park, Woo-Jung (Charmzone R&D Center, Charmzone Cosmetic, Ltd.) Um, Sang-Young (Charmzone R&D Center, Charmzone Cosmetic, Ltd.) Lee, Dae-Woo (R&D Center, DERMALAB Co. Ltd.) Kang, Sang-Mo (Department of Microbial Engineering, Konkuk university) |
1 | Beissert, S. and R. Granstein (1996) UV-induced cutaneous photobiology. Crit. Rev. Biochem. Mol. Biol. 31: 381-404. DOI ScienceOn |
2 | Sen, R. and D. Baltimore (1988) Inducibility of kappa immunoglobulin enhancer-binding protein NF-kappa B by a posttranslational mechanism. Cell 47: 921-928. |
3 | Lin, A. and M. Karin (2003) NF-kB in cancer: a marked target. Semin. Cancer Biol. 13: 107-114. |
4 | Kim, D. and J. Chung (2002) Akt: versatile mediator of cell survival and beyond. J. Biochem. Mol. Biol. 35: 106-115. 과학기술학회마을 DOI |
5 | Alessi, D. R., Y. Saito, D. G. Campbell, P. Cohen, G. Sithanandam, and U. Rapp (1994) Ashworth A, Marshall CJ, Cowley S, Identification of the sites in MAP kinase kinase-1 phosphorylated by p74 raf-1. EMBO J. 13:1610-1619. |
6 | O'Shea, J. J., M. Gadina, and R. D. Schreiber (2002) Cell. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. 109: S121-S131. DOI ScienceOn |
7 | Raingeaud, J., S. Gupta, J. S. Rogers, M. Dickens, J. Han, R. J. Ulevitch, and R. J. Davis (1995) Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270: 7420-7426. DOI ScienceOn |
8 | Zarubin, T. and J. Han (2005) Activation and signaling of the p38 MAP kinase pathway. Cell Res. 15: 11-18. DOI |
9 | Roux, P. P. and J. Blenis (2004) ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 68: 320-344. DOI ScienceOn |
10 | Melnikova, V. O. and H. N. Ananthaswamy (2005) Cellular and molecular events leading to the development of skin cancer. Mutation Research 571: 91-106. DOI ScienceOn |
11 | Matsumura Y. and H. N. Ananthaswamy (2004) Toxic effects of ultraviolet radiation on the skin. Toxicol Applied Pharmacol 195: 298-308. DOI ScienceOn |
12 | Enomoto, S., K. Yanaoka, H. Utsunomiya, T. Niwa, K. Inada, H. Deguchi, K. Ueda, C. Mukoubayashi, I. Inoue, T. Maekita, K. Nakazawa, M. Iguchi, K. Arii, H. Tamai, N. Yoshimura, M. Fujishiro, M. Oka, and M. Ichinose (2010) Inhibitory effects of Japanese apricot (Prunus mume Siebold et Zucc.; Ume) on Helicobacter pylori-related chronic gastritis. Eur. J. Clin. Nutr. 64: 714-719. DOI ScienceOn |
13 | Bode, A. M. and Z. Dong (2003) Mitogen-activated protein kinase activation in UV-induced signal transduction. Sci STKE RE2. |
14 | Smith, W. L., D. L. DeWitt, and R. M. Garavito (2002) Cyclooxygenases: structural, cellular, and molecular biology. Ann. Rev. Biochem. 69: 145-182. |
15 | Chuda, Y., H. Ono, M. Ohnishi-Kameyama, K. Matsumoto, T. Nagata, and Y. Kikuchi (1999) Mumefural, citric acid derivative improving blood fluidity from fruit-juice concentrate of Japanese apricot (Prunus mume Sieb. et Zucc). J. Agric. Food Chem. 47: 828-831. DOI ScienceOn |
16 | Kim, B. J., J. H. Kim, H. P. Kim, and M. Y. Heo (1997) Biological screening of 100 plant extracts for cosmetic use (II): anti-oxidative activity and free radical scavenging activity. Int. J. Cosmet. Sci. 19: 299-307. DOI ScienceOn |
17 | Miyazawa, M., H. Utsunomiya, K. Inada, T. Yamada, Y. Okuno, H. Tanaka, and M. Tatematsu (2006) Inhibition of Helicobacter pylori motility by (+)-Syringaresinol from unripe Japanese apricot. Biol. Pharm. Bull. 29: 172-173. DOI |
18 | Nakajima, S., K. Fujita, Y. Inoue, M. Nishio, and Y. Seto (2006) Effect of the folk remedy, Bainiku-ekisu, a concentrate of Prunus mume juice, on Helicobacter pylori infection in humans. Helicobacter. 11: 589-591. DOI ScienceOn |
19 | Yu, H., D. Pardoll, and R. Jove (2009) STATs in cancer inflammation and immunity: a leading role for STAT3. Nat. Rev. Cancer 9: 798-809. DOI ScienceOn |
20 | Tsuji, R., H. Koizumi, and D. Fujiwara (2011) Effects of a plum (Prunus mume Siebold and Zucc.) ethanol extract on the immune system in vivo and in vitro. Biosci. Biotechnol. Biochem. 75: 2011-2013. DOI ScienceOn |
21 | Gao, H. and P. A. Ward (2007) STAT3 and suppressor of cytokine signaling 3: potential targets in lung inflammatory responses. Expert Opin. Ther. Targets 11: 869-880. DOI ScienceOn |
22 |
Andrs, R. M., M. C. Montesinos, P. Navaln, M. Pay, and M. C. Terencio (2013) NF- |
23 | Setlow, R. B. (1974) The wavelengths in sunlight effective in producing skin cancer: a theoretical analysis. Proc. Natl. Acad. Sci. USA 71: 3363-3366. DOI ScienceOn |
24 | Alessi, D. R., M. Andjelkovic, B. Caudwell, P. Cron, N. Morrice, P. Cohen, and B. A. Hemmings (1996) Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15: 6541-6551. |
25 | Sarbassov, D. D., D. A. Guertin, S. M. Ali, and D. M. Sabatini (2005) Phosphorylation and regulation of Akt/PKB by the rictormTOR complex. Science 307: 1098-1101. DOI |
26 | Ley, R. D. (1974) Photoreactivation in humans. Proc. Natl. Acad. Sci. USA 90: 4337. |
27 | Hess, J., P. Angel, and M. Schorpp-Kistner (2004) AP-1 subunits: quarrel and harmony among siblings. J. Cell. Sci. 117: 5965-5973. DOI ScienceOn |
28 | Lee, J. L., H. Mukhtar, D. R. Bickers, L. Kopelovich, and M. Athar (2003) Cyclooxygenases in the skin: pharmacological and toxicological implications. Toxicol. Applied Pharmacol. 192: 294-306. DOI ScienceOn |
29 | Ameyar, M., M. Wisniewska, and J. B. Weitzman (2003) A role for AP-1 in apoptosis: the case for and against. Biochimie 85: 747-752. DOI ScienceOn |
30 | Fischer, S. M., H. H. Lo, and G. B. Gordon (1999) Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis. Mol. Carcinog. 25: 231-240. DOI |
31 | Karin, M. (1998) Mitogen-activated protein kinase cascades as regulators of stress responses. Ann. NY Acad. Sci. 851: 139-146. DOI |
32 | Jacinto, E., V. Facchinetti, D. Liu, N. Soto, S. Wei, S. Y. Jung, Q. Huang, J. Qin, and B. Su (2006) SIN1/MIP1 maintains rictormTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127: 125-137. DOI ScienceOn |
33 | DiDonato, J. A., M. Hayakawa, D. M. Rothwarf, E. Zandi, and M. A. Karin (1997) cytokine-responsive IkB kinase that activates the transcriptional factor NF-kB. Nature 388: 548-554. DOI ScienceOn |
34 | Chen, W., Q. Tang, M. S. Gonzales, and G. T. Bowden (2001) Role of p38 MAP kinases and ERKin mediating ultraviolet-B induced cyclooxygenase-2 gene expression in human keratinocytes. Oncogene. 20: 3921-3926. DOI ScienceOn |
35 | Ding, M., R. Feng, and S. Y. Wang (2006) Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity. J. Biol. Chem. 281: 17359-17368. DOI ScienceOn |
36 | Matsumuram Y. and H. Ananthaswamy (2002) Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicine. Expert Rev. Mol. Med. 26: 1-22. |
![]() |