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http://dx.doi.org/10.7841/ksbbj.2012.27.4.243

Effect of Feedstuffs on Mineral Composition, Antioxidant Capacity, and Protection of Neuronal PC-12 Cells of Deer Antlers  

Cho, Chi-Heung (Department of Food Science and Biotechnology and Institute of Life Sciences and Resources, Kyung Hee University)
Lee, Bong-Han (Department of Food Science and Biotechnology and Institute of Life Sciences and Resources, Kyung Hee University)
Kim, Hae-Yeong (Department of Food Science and Biotechnology and Institute of Life Sciences and Resources, Kyung Hee University)
Kim, Young-Chae (Department of Ecosystem Engineering, Kyung Hee University)
Kim, Dae-Ok (Department of Food Science and Biotechnology and Institute of Life Sciences and Resources, Kyung Hee University)
Publication Information
KSBB Journal / v.27, no.4, 2012 , pp. 243-250 More about this Journal
Abstract
The ash content, mineral composition, total phenolics, antioxidant capacity, and neuroprotective effect of the antlers of deer fed with herb-incorporated feedstuff (HFS) or normal feedstuff (NFS) were comparatively evaluated. The contents of ash and mineral of the antler of deer fed with HFS were significantly lower than its counterpart. The ash and mineral contents of deer antlers decreased generally from the upper section toward the tip section. The ratios of Ca/ash, Ca/P, and Ca/Fe of antler of deer fed with HFS were lower than those of antler of deer fed with NFS. Antlers of deer fed with HFS had higher total phenolics, nitrite scavenging capacity, and antioxidant capacity than those of deer fed with NFS. Antlers of deer fed with HFS or NFS showed in vitro neuronal protection of PC-12 cells against oxidative stress in a dose-dependent manner, where antler of deer fed with HFS generally had higher cellular viability than NFS. These results above suggest that the incorporation of the medicinal herbal complex into feedstuff may improve the biological effects of deer antlers.
Keywords
Anti-neurodegenerative effect; Ash; Lactate dehydrogenase release; Oxidative stress; Total phenolics;
Citations & Related Records
Times Cited By KSCI : 16  (Citation Analysis)
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