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http://dx.doi.org/10.7841/ksbbj.2012.27.2.109

Enhancement of the Stability and Solubility of Prodigiosin Using β-Cyclodextrin in Seawater  

Park, Hee-Yong (Division of Polar Life Sciences, Korea Polar Research Institute, KORDI)
Kim, Tai-Kyoung (Division of Polar Life Sciences, Korea Polar Research Institute, KORDI)
Han, Se-Jong (Division of Polar Life Sciences, Korea Polar Research Institute, KORDI)
Yim, Joung-Han (Division of Polar Life Sciences, Korea Polar Research Institute, KORDI)
Publication Information
KSBB Journal / v.27, no.2, 2012 , pp. 109-113 More about this Journal
Abstract
This research was to examine the effects of various cyclodextrins on the solubility and stability of prodigiosin in seawater. Among them, ${\beta}$-cyclodextrin was found to have the best efficiency and formation of the inclusion complex was saturated when prodigiosin and ${\beta}$-cyclodextrin were mixed in a ratio of 1:8 and shaken at $25^{\circ}C$ and pH 8.0 for 6 h. The maximum algicidal activity against Chattonella antiqua using the inclusion complex stored at $4^{\circ}C$ for 5 weeks of culture was obtained, $52.28{\pm}3.41%$, which was about 5.0 fold higher than that of control. Our results suggest that inclusion complexes of prodigiosin and ${\beta}$-cyclodextrin could serve as effective algicidal agents.
Keywords
Algicidal activity; Chattonella antiqua; Cyclodextrin; Inclusion complex; Prodigiosin;
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Times Cited By KSCI : 1  (Citation Analysis)
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