Protein Analysis of Bacillus subtilis MORI 3K-85 with Reference to the Biosynthesis of 1-Deoxynojirimycin
![]() |
Cho, Yong-Seok
(Department of Life Science, The University of Suwon)
Kang, Kyung-Don (R&D center for Life Science, Biotopia Co., Ltd.) Park, Young-Shik (R&D center for Life Science, Biotopia Co., Ltd.) Lee, Jae-Yeon (R&D center for Life Science, Biotopia Co., Ltd.) Kim, Hyun-Su (Department of Life Science, The University of Suwon) Yuk, Won-Jeong (R&D center for Life Science, Biotopia Co., Ltd.) Kamita, Shizuo George (Department of Entomology, University of California) Hwang, Kyo-Yeol (R&D center for Life Science, Biotopia Co., Ltd.) Seong, Su-Il (Department of Life Science, The University of Suwon) |
1 | Kang, K.-D., Y. S. Cho, J. H. Song, Y. S. Park, J. Y. Lee, K. Y. Hwang, S. K. Rhee, J. H. Chung, O. Kwon, and S. I. Seong (2011) Identification of the gene involved in 1-deoxynojirimycin synthesis in Bacillus subtilis MORI 3K-85. J. Microbiol. 49: 431-440. DOI |
2 | Cho, Y. S. (2011) Studies on 1-deoxynojirimycin biosynthesis genes in Bacillus subtilis MORI. Ph.D. Thesis. University of Suwon, Hwaseong-si, Gyeonggi-do, Korea. |
3 | Bollag, D. M., M. D. Rozycki, and S. J. Edelstein (1996) Protein Methods: Gel Electrophoresis Under Denaturing Conditions and Gel Electrophoresis Under Nondenaturing Conditions. 2nd ed., pp. 107-172. Wiley-Liss Inc., NY, USA. |
4 | Berkelman, T. and T. Stenstelt (2002) 2-D Electrophoresis Using Immobilized pH Gradie-nts, Principles and Methods. 2nd ed., pp. 17-93. Amersham Biosciences, Uppsala, Sweden. |
5 | Hardick, D. J. and D. W. Hutchinson (1993) The biosynthesis of 1-deoxynojirimycin in Bacillus subtilis var niger. Tetrahedron 49: 6707-6716. DOI ScienceOn |
6 | Hardick, D. J., D. W. Hutchinson, S. J. Trew, and E. M. H. Wellington (1992) Glucose is a precursor of 1-deoxynojirimycin and 1-deoxymannonojirimycin in Streptomyces subrutilus. Tetrahedron 48: 6285-6296. DOI ScienceOn |
7 | Shibano, M., Y. Fujimoto, K. Kushino, G. Kusano, and K. Baba (2004) Biosynthesis of 1-deoxynojirimycin in Commelina communis: a difference between the microorganisms and plants. Phytochemstry 65: 2661-2665. DOI ScienceOn |
8 | Clark, L. and N. Horenstein (2010) Biosynthesis of Azasugars. First Southeast Enzyme Conference. April 10. Atlanta, GA, USA. |
9 | Watson, A. A., G. W. G. Fleet, N. Asano, R. J Molyneux, and R. J. Nash (2001) Polyhydroxylated alkaloids-natural occurrence and therapeutic applications. Phytochemistry 56: 265-295. DOI ScienceOn |
10 | Asano, N., R. J. Nash, R. J. Molyneux, and G. W. J. Fleet (2000) Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application. Tetrahedron: Asymmetry 53: 1645-1680. |
11 | Schedel, M. (2008) Regioselective Oxidation of Aminosorbitol with Gluconobacter oxydans, Key Reaction in the Industrial 1-Deoxynojirimycin Synthesis, pp. 296-307. In: H.-J. Rehm and G. Reed (eds.), Biotechnology: Biotransformations II, Volume 8b, 2nd ed. Wiley-VCH Verlag GmbH, Weinheim, Germany. |
12 | Asano, N., K. Oseki, E. Tomioka, H. Kizu, and K. Matsui (1994) N-containing sugars from Morus alba and their glycosidase inhibitory activities. Carbohyr. Res. 259: 243-255. DOI ScienceOn |
13 | Asano, N., T. Yamashita, K. Yasuda, K. Ikeda, H. Kizu, Y. Kameda, A. Kato, R. J. Nash, H. S. Lee, and K. S. Ryu (2001) Polyhydroxylated alkaloids isolated from mulberry trees (Morus alba L.) and silkworms (Bombyx mori L.). J. Agric. Food Chem. 49: 4208-4213. DOI ScienceOn |
14 |
Yoshikuni, Y. (1988) Inhibition of intestinal |
15 | Gruters, R. A., J. J. Neefjes, M. Tersmette, R. E. Y. D. Goede, A. Tulp, H. G. Huisman, F. Miedema, and H. L. Ploegh (1987) Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase. Nature 330: 74-77. DOI ScienceOn |
16 | Fleet, G. W. J., A. Karpas, R. A. Dwek, L. E. Fellows, A. S. Tyms, S. Petursson, S. K. Namgoong, N. G. Ramsden, P. W. Smith, J. C. Son, F. Wilson, D. R. Witty, G. S. Jacob, and T. W. Rademacher (1988) Inhibition of HIV replication by amino-sugar derivatives. FEBS Lett. 237: 128-132. DOI |
17 | Karpas, A., G. W. J. Fleet, R. A. Dwek, S. Petursson, S. K. Namgoong, N. G. Ramsden, G. S. Jacob, and T. W. Rademacher (1988) Aminosugar derivatives as potential anti-human immunodeficiency virus agents. Proc. Natl. Acad. Sic. USA 85: 9229-9233. DOI ScienceOn |
18 |
Mehta, A., N. Zitzmann, P. M. Rudd, T. M. Block, and R. A. Dwek (1998) |
19 | Dwek, R. A., T. D. Butters, F. M. Platt, and N. Zitzmann (2002) Targeting glycosylation as a therapeutic approach. Nat. Rev. Drug. Discov. 1: 65-75. DOI |
20 | Jacob, J. R., K. Mansfield, J. E. You, B. C. Tennant, and Y. H. Kim (2007) Natural iminosugar derivatives of 1-deoxynojirimycin inhibit glycosylation of hepatitis viral envelope proteins. J. Microbiol. 45: 431-440. |
21 |
Kim, H. S., J. Y. Lee, K. Y. Hwang, Y. S. Cho, Y. S. Park, K.-D. Kang, and S. I. Seong (2011) Isolation and identification of a Bacillus sp. producing |
22 | Afarinkia, K. and A. Bahar (2005) Recent advances in the chemistry of azapyranose sugars. Tetrahedron: Asymmetry 16: 1239-1287. DOI ScienceOn |
23 | Cho, Y. S., Y. S. Park, J. Y. Lee, K.-D. Kang, K. Kim, K. Y. Hwang, and S. I. Seong (2008) Hypoglycemic effect of culture broth of Bacillus subtilis S10 producing 1-deoxynojirimycin. J. Korean Soc. Food Sci. Nutr. 37: 1401-1407. DOI |
24 | Stein, D. C., L. K. Kopec, R. E. Yasbin, and F. E. Young (1984) Characterization of Bacillus subtilis DSM704 and its production of 1-deoxynojirimycin. Appl. Environ. Microbiol. 48: 280-284. |
25 | Ezure, Y., S. Maruo, K. Miyazaki, and M. Kawamata (1985) Moranoline (1-deoxynojirimycin) fermentation and its improvement. Agric. Biol. Chem. 49: 1119-1125. DOI |
26 | Hardick, D. J., D. W. Hutchinson, S. J. Trew, and E. M. H. Wellington (1991) The biosynthesis of deoxynojrimycin and deoxymannonojirimycin in Streptomyces subrutilus. J. Chem. Soc. Chem. Commun. 10: 729-730. |
![]() |