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Effect of Complex Extracts of Mushroom and Sharp Toothed Eel on the Skin Conditions with Atopic Dermatitis and Acne Symptoms  

Cha, Wol-Suk (Department of Biochemical Engineering, Chosun University)
Yoo, Ji-Hyun (Department of Biochemical Engineering, Chosun University)
Min, Myung-Ja (Department of Biochemical Engineering, Chosun University)
Nam, Hyung-Gun (Department of Biochemical Engineering, Chosun University)
Kim, Yun-Soo (Department of Biochemical Engineering, Chosun University)
Shin, Hyun-Jae (Department of Biochemical Engineering, Chosun University)
Kim, Jong-Soo (Division of Chemical Engineering, Chonbuk National University)
Choi, On-You (Department of Environmental health, Cho-dang University)
Kim, Ran (Department of Cosmetology, Wonkwang Health Science University)
Choi, Du-Bok (Biotechnology Lab, BK Company R&D center)
Publication Information
KSBB Journal / v.25, no.4, 2010 , pp. 387-394 More about this Journal
Abstract
This study was conducted to investigate effect of complex extract of various mushrooms and sharp toothed eel on the skin conditions with atopic dermatitis and acne symptoms. The total phenol concentration was increased in order of hot water> ethanol> ethyl acetate> petroleum ether> chloroform extract. Especially, when the hot water extract was used, it was about 2-3 fold higher than that of ethyl acetate, petroleumether, and chloroform extract. When the complex extract concentration was increased from 1.0 to 50 mg/L, the DPPH scavenging rate increased from 10.1 to 81.4%. The reduction power was sharply increased from 0.05 to 0.27 (700 nm) when the complex extract concentration was increased from 25 to 75 mg/L. However, above 100 mg/L, it was not decreased. In the case of SOD-like activity, it was 45.7% at 100 mg/L. Total numbers of patients with atopic dermatitis were 15 and 5 patients with severe acne symptoms. According to photos taken before and after the treatment and questionnaire results, considerable improvements in skin conditions are observed in the patients with atopic dermatitis and acne. For atopic patients, erythema and edema have been improved but the degree of effect was dependent on the individual's constitution. Concerning acne, the effect of coating of the extracts was prominent for first week and the degree decreased with time till 4 weeks. The complex extracts wereefficient in soothing rash and maturation. Side effects such as a scar were not detected during the application and treatment.
Keywords
mushroom; sharp toothed eel; antioxidant; atopic dermatitis; acne;
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Times Cited By KSCI : 1  (Citation Analysis)
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