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Preparation of PEG Microparticles Containing Coriander Essential Oil Using Supercritical PGSS Process  

Choi, Jin-Ah (Department of Chemical Engineering, The University of Suwon)
Lim, Gio-Bin (Department of Chemical Engineering, The University of Suwon)
Ryu, Jong-Hoon (Department of Chemical Engineering, The University of Suwon)
Publication Information
KSBB Journal / v.25, no.4, 2010 , pp. 379-386 More about this Journal
Abstract
In the present study, biocompatible poly (ethylene glycol) (PEG) microparticles containing coriander essential oil were prepared using a supercritical particles from gas saturated solution (PGSS) process to improve the stability of the coriander oil. The effects of various process parameters such as temperature, pressure, and nozzle diameter on the morphology and entrapment efficiency of coriander oil loaded PEG microparticles were then investigated. A positive influence on the formation of spherical microparticles was observed with increasing temperature and decreasing pressure. Furthermore, somewhat more porous microparticles were produced with an increase in pressure. At a given temperature, the highest entrapment efficiency of coriander essential oil in PEG microparticles was observed under the lowest experimental pressure condition.
Keywords
PGSS; coriander essential oil; supercritical fluid; microparticle;
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1 Lee, S. O., G. J. Choi, K. S. Jang, H. K. Lim, K. Y. Cho, and J. C. Kim (2007) Antifungal activity of five plant essential oils as fumigant against postharvest and soilborne plant pathogenic fungi. Plant Pathol. J. 23: 97-102.   과학기술학회마을   DOI
2 Gallagher, A. M., P. R. Flatt, G. Duffy, and Y. H. A. Abdel-Wahab (2003) The effects of traditional antidiabetic plants on in vitro glucose diffusion. Nutr. Res. 23: 413-424.   DOI   ScienceOn
3 Weidner, E., V. Wiesmet, Z. Knez, and M. Serget (1997) Phase equilibrium (solid-liquid-gas) in polyethyleneglycolcarbon dioxide systems. J. Supercrit. Fluids 10: 139-147.   DOI   ScienceOn
4 Menichini, F., F. Conforti, D. Rogano, C. Formisano, F. Piozzi, and F. Senatore (2009) Phytochemical composition, anti-inflammatory and antitumour activities of four Teucrium essential oils from Greece. Food Chem. 115: 679-686.   DOI   ScienceOn
5 York, P. (1999) Strategies for particle design using supercritical fluids. Pharm. Sci. Technol. Today 2: 430-440.   DOI   ScienceOn
6 Seo, H. Y., K. M. No, S. L. Shim, K. Y. Ryu, K. J. Han, R. Gyawali, and K. S. Kim (2006) Analysis of enantiomeric composition of chiral flavor components from dried ginger (Zingiber officinale Roscoe). J. Korean Soc. Food Sci. Nutr. 35: 874-880.   과학기술학회마을   DOI
7 Wendt, T., G. Brandin, E. Weidner, and M. Petermann (2007) PGSS - The innovative production of fluid-filled microcapsules for the food industry. Proceedings of European Congress of Chemical Engineering (ECCE-6). September 16-20. Copenhagen, Denmark.
8 Illes, V., H. G. Daood, S. Perneczki, L. Szokonya, and M. Then (2000) Extraction of coriander seed oil by $CO_{2}$ and propane at super- and subcritical conditions. J. Supercrit. Fluids 17: 177-186.   DOI   ScienceOn
9 Heikki, K. and K. Kerrola (1992) Application of liquid carbon dioxide to the extraction of essential oil of coriander (Coriandrum sativum L.) fruits. Z Lebensm Unters Forsch 195: 545-549.   DOI
10 Choi, H. S. and M, Sawamura (2001) Volatile flavor components of ripe and overripe ki-mikans (Citrus flaviculpus Hort. ex Tanaka) in comparison with hyuganatsu (Citrus tamurana Hort. ex Tanaka). Biosci. Biotechnol. Biochem. 65: 48-55.   DOI   ScienceOn
11 Babushok, V. I. and L. G (2009) Zenkevich, Retention indices for most frequently reported essential oil compounds in GC. Chromatographia 69: 257-269.   DOI
12 Kim, S. H., and S. H. Kim (2007) Biofunctional biodegradable polymers. Polym. Sci. Technol. 18: 450-457.
13 Goodner, K. L. (2008) Practical retention index models of OV-101, DB-1, DB-5, and DB-Wax for flavor and fragrance compounds. LWT - Food Sci. Technol. 41: 951-958.   DOI   ScienceOn
14 Wangensteen, H., A. B. Samuelsen, and K. E. Malterud (2004) Antioxidant activity in extracts from coriander. Food Chem. 88: 293-297.   DOI   ScienceOn
15 Chithra, V. and S. Leelamma (2000) Coriandrum sativum - effect on lipid metabolism in 1,2-dimethyl hydrazine induced colon cancer. J. Ethnopharmacol. 71: 457-463.   DOI   ScienceOn
16 Park, K. K. and D. W. Pack (2005) Biodegradable polymers for microencapsulation of drugs. Molecules 10: 146-161.   DOI   ScienceOn
17 Jamie, L. O. (2006) PEG-based degradable networks for drug delivery applications. Ph. D. Thesis. Drexel University, Philadelphia. USA.
18 Fuertges, F. and A. Abuchowski (2009) The clinical efficacy of poly(ethylene glycol)-modified proteins. J. Control. Release 11: 139-148.
19 Hong, E. J., K. J. Na, I. G. Choi, K. C. Choi, and E. B. Jeung (2004) Antibacterial and antifungal effects of essential oils from coniferous trees. Biol. Pharm. Bull. 27: 863-866.   DOI   ScienceOn
20 Yoo, M. K., J. H. Park, and S. Y. Jeon (2008) Magnetic resonance imaging nano-agents for cancer imaging. Polym. Sci. Technol. 19: 116-124.
21 Svoboda, K. P., and J. B. Hampson (1999) Bioactivity of essential oils of selected temperate aromatic plants: antibacterial, antioxidant, antiinflammatory and other related pharmacological activities. In: Special Chemicals for the 21st Century. ADEME/IENICA International Seminar. September 16-17. Paris, France.
22 Prabuseenivasan, S., M. Jayakumar, and S. Ignacimuthu (2006) In vitro antibacterial activity of some plant essential oils. BMC Complementary and Alternative Medicine 30: 6-39.
23 Randrianarivelo, R., S. Sarter, E. Odoux, P. Brat, M. Lebrun, B. Romestand, C. Menut, H. S. Andrianoelisoa, M. Raherimandimby, and P. Danthu (2009) Composition and antimicrobial activity of essential oils of Cinnamosma fragrans. Food Chem. 114: 680-684.   DOI   ScienceOn
24 Ebrahimi, S. N., J. Hadian, M. H. Mirjalili, A. Sonboli, and M. Yousefzadi (2008) Essential oil composition and antibacterial activity of Thymus caramanicus at different phenological stages. Food Chem. 110: 927-931.   DOI   ScienceOn
25 Hao, J., M. J. Whitaker, G. Serhatkulu, K. M. Shakesheff, and S. M. Howdle (2005) Supercritical fluid assisted melting of poly(ethylene glycol): a new solvent free route to microparticles. J. Mater. Chem. 15: 1148-1153.   DOI   ScienceOn
26 Emamghoreishi, M., M. Khasaki, and M. F. Aazam (2005) Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J. Ethnopharmacol. 96: 365-370.   DOI   ScienceOn
27 Msaada, K., K. Hosni, M. B. Taarit, T. Chaged, M. E. Kchouk, and B. Marzouk (2007) Changes on essential oil composition of coriander (Coriandrum sativum L.) fruits during three stages of maturity. Food Chem. 102: 1131-1134.   DOI   ScienceOn
28 Nalawade, S., P. F. Picchion, and L. P. B. M. Janssen (2007) Batch production of micron size particles from poly(ethylene glycol) using supercritical $CO_{2}$ as a processing solvent. Chem. Eng. Sci. 62: 1712-1720.   DOI   ScienceOn
29 Byrappa, K., S. Ohara, and T. Adschiri (2008) Nanoparticles synthesis using supercritical fluid technology-towards biomedical applications. Adv. Drug Deliv. Rev. 60: 299-327.   DOI   ScienceOn
30 Song, E. S., H. S. Jung, H. H. Lee, J. D. Kim, H. Y. Kim, and Y. W. Lee (2006) The Production of protein-loaded poly(lactide-co-glycolide) microparticles using supercritical carbon dioxide. Clean Technology 12: 53-61.
31 Jung, J. H., I. I. Jung, H. J. Joo, J. R. Shin, G. B. Lim and J. H. Ryu (2008) Preparation of biodegradable polymer microparticles containing 5-FU using supercritical carbon dioxide. KSBB J. 23: 452-459.   과학기술학회마을
32 Bakkali, F., S. Averbeck, D. Averbeck, and M. Idaomar (2008) Biological effects of essential oils - A review. Food Chem. Toxicol. 46: 466-475.
33 Shigeharu, I., T. Toshio, and Y. Hidetyo (2001) Antibacterial activity of essential oils and their major constituents against respiratory tract pathogens by gaseous contact. J. Antimicrob. Chemother. 47: 565-573.   DOI
34 Shittu, L. A. J., M. A. Bankole, T. Ahmed, M. N. Bankole, R. K. Shittu, C. L. Saalu, and O.A. Ashiru (2007) Antibacterial and antifungal activities of essential oils of crude extracts of sesame radiatum against some common pathogenic micro-organisms. IJPT 6: 165-170.
35 Kim, D. H., H. J. Park, S. H. Kang, S. W. Jun, M. S. Kim, S. B. Lee, J. S. Park, and S. J. Hwang (2005) Preparation and characterization of lysozyme nanoparticles using solution enhanced dispersion by supercritical fluid (SEDS) Process. J. Kor. Pharma. Sci. 35: 89-94.   과학기술학회마을
36 Stefano, S., N. Elvassore, A. Bertucco and P. Caliceti (2009) Production of solid lipid submicron particles for protein delivery using a novel supercritical gasassisted melting atomization process. J. Pharm. Sci. 98: 640-650.   DOI   ScienceOn
37 Lee, Y. W. (2003) Design of particles using supercritical fluids. HWAHAK KONGHAK 41: 679-688.
38 Tandya, A., F. Dehghani, and N. R. Foster (2006) Micronization of cyclosporine using dense gas techniques. J. Supercrit. Fluids 37: 272-278.   DOI   ScienceOn
39 Rodrigues, M., N. Peirico, H. Matos, E. G. de Azevedo, M. R. Lobato, and A. J. Almeida (2004) Microcomposites theophylline/hydrogenated palm oil from a PGSS process for controlled drug delivery systems. J. Supercrit. Fluids 29: 175-184.   DOI