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In Vitro Glucose and Bile Acid Retardation Effect of Fucoidan from Laminaria japonica  

Park, Kap-Yong (Department of Bioengineering and Technology, Kangwon National University)
Back, Jin-Hong (KJM Aloe R&D Center)
Hur, Won (Department of Bioengineering and Technology, Kangwon National University)
Lee, Shin-Young (Department of Bioengineering and Technology, Kangwon National University)
Publication Information
KSBB Journal / v.22, no.4, 2007 , pp. 265-269 More about this Journal
Abstract
Fucoidan from sea tangle (Laminaria japonica) was isolated by hot water extraction, and partially purified. The in-vitro glucose and bile acid retarding effects of the partially purified fucoidan were investigated. Fucoidan exhibited 27.06$\sim$21.42% of retarding index for glucose and 33.50$\sim$27.02% of retarding index for bile acid during in vitro dialysis experiment for 2 hours. These retarding effects on glucose and bile acid diffusion was considered as a relatively good or very good, suggesting the prevention from diabetes and arteriosclerosis of some extent.
Keywords
Fucoidan; Laminaria japonica; in-vitro glucose and bile acid retarding effect;
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