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The Effects of Extracts from Ginseng, Wormwood and Pine needle in Pulmonary Structure and Anti-oxidant Enzyme in Smoking  

Jung, Hyuk (Department of Biochemistry, Kyungpook National University)
Kim, Sang-Ki (Department of Biochemistry, Kyungpook National University)
Kim, Sang-Guk (Department of Biochemistry, Kyungpook National University)
Sung, Mi-Young (Department of Biochemistry, Kyungpook National University)
Kim, Hyun-Jung (Department of Biochemistry, Kyungpook National University)
Kim, Bum-Hak (Department of Biochemistry, Kyungpook National University)
Kim, Yu-Young (Department of Biochemistry, Kyungpook National University)
Publication Information
KSBB Journal / v.19, no.2, 2004 , pp. 138-142 More about this Journal
Abstract
Cigarette smoke causes atypical structure of pulmonary (cell structural) and oxidative damage. Therefore, we carried out to determine if exposure to cigarette smoke alters pulmonary structure and anti-oxidant related enzyme in a ICR mice model, when natural product extracts using by manual sprayer. The mice were divided into five groups, control group, sham-treated group (Sham), natural product extracts-treated group (NPE), natural product extracts-treated with smoke-exposed group (NPE-SM) and smoke-exposed (SM) group. All groups are similar to control group in weight, but SM group is lower than the other groups. Microscopic image of the pulmonary structure in SM group showed deleterious alterations in the morphology, but the other groups are maintained in original structure. In anti-oxidant related enzyme, SOD (superoxide dismutase) and catalase, SM group represents the lowest enzyme activity among all groups. These results indicate that the natural product extracts is an efficient tissue protective agent against smoke-induced lung injury.
Keywords
Ginseng; wormwood; pine needle; pulmonary; smoking; morphology; anti-oxidant;
Citations & Related Records
Times Cited By KSCI : 4  (Citation Analysis)
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1 Toxicologic considerations in workplace exposures /
[ Burton,B.T. ] / Allergy. Clin. North Am.   ScienceOn
2 Indoor pollution and its impact on respiratory health /
[ Bardana,E.J.Jr. ] / Ann. Allergy Asthma. Immunol.
3 Failure of cigarette smoke to induce or promote lung cancer in the A/J mouse /
[ Finch,G.L.;K.J.Nikula;S.A.Belinsky;E.B.Barr;G.D.Stoner;J.F.Lechner ] / Cancer letter   ScienceOn
4 Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease /
[ Rahman,I.;W.I.Macnee ] / Am. J. Physiol.
5 Smoking and pregnancy /
[ Bol,P. ] / Ned. Tijdschr. Tandheelkd
6 The difference ginsenoside compositions according to the conditions of extraction and fractionation of crude ginseng saponins /
[ Shin,J.Y.;E.H.Choi;J.J.Wee ] / Kor. J. Food Sci. Technol.
7 13-Week Inhalation toxicity study of menthol cigarette smoke /
[ Gaworski,C.L.;M.M.Dozier;L.M.Gerhart;N.Ralendran;L.H.Brennec;C.Aranyi;J.D.Heck ] / Chemical. Toxicology   ScienceOn
8 Oxidants, Nitrosants, and the Lung /
[ Vlie,A.V.D.;E.Carroll ] / Am. J. Med.   ScienceOn
9 Clinical application and efficacy of korea ginseng (Panax ginseng C.A. Meyer) /
[ Yeul,N.K. ] / J. Ginseng Res.
10 Occupational asthma due to exposure to iroko wood dust /
[ Ricciardi,L.;R.Fedele;S.Saitta;V.Tigano;L.Mazzero;O.Fogliani;D.Barber;S.Isola ] / Ann. Allergy. Asthma. Immunol.   ScienceOn
11 Effect of pine needle extract on Fe ion and active oxygen related lipid oxidation in oil emulsion /
[ Kim,S.M.;Y.S.Cho ] / Kor. J. Postharvest Sci. Technol.   과학기술학회마을
12 Effects of depletion of Effects of depletion of neutrophils or macrophages on development of cigarette smoke-induced emphysema /
[ Ofulue,A.;M.K.Felix ] / Am. J. Physiol.;Lung Cell. Mol. Physiol.
13 Modulation of cigarette smoke-related end-points in mutagenesis and carcinogenesis /
[ Flora,S.D.;F.D'A;R.Balansky;A.Camoirano;C.Bennicelli;M.Bagnasco;C.Cartiglia;E.Tampa;M.G.Longobardi;R.A.Lubet;A.Izzotti ] / Mutation Research
14 Alteration of pulmonary surfactant proteins in rats chronically exposed to cigarette smoke /
[ Subrammaniam,S.;J.A.Whitsett;W.Hull;C.G.Gairola ] / Toxicology. Appl. Phamacol   ScienceOn
15 Smoking-induced elevations in blood carboxyhaemo-globin levels /
[ McDonough,P.;R.J.Moffatt ] / Sports Med.   ScienceOn
16 Inhibition effect of artemisia princeps Pampan extract on growth of cancer cell line /
[ Hwnag,Y.K.;D.C.Kim;W.I.Hwang;Y.B.Han ] / The Korean Nutrition Society   과학기술학회마을
17 Cigarette smoking and lung cancer chemical mechanisms and approaches to prevention /
[ Hecht,S.S. ] / Lancet. Oncol.   ScienceOn
18 Occupational asthma caused by exposure to low-molecular-weight chemicals /
[ Bernstein,D.I. ] / Immunol. Allergy. Clin. North Am.   ScienceOn
19 Antioxidant action of ginseng: an hypothesis /
[ Lee,D.W.;H.B.Sohn;H.B.Lim;Y.G.Lee ] / Kor. J. Ginseng Sci.   과학기술학회마을
20 Air pollution and respiratory pathology: lung cancer /
[ Caputi,M.;V.Esposito;A.Mancini;A.Giordano ] / Monaldi Arch Chest Dis.
21 Relationship of jute dust to interstitial fibrosis in rat lung /
[ Chen,J.;X.Wang;J.Lou;Z.Liu ] / Arch. Environ. Health   ScienceOn
22 Inflammatory bio-markers and cardiovascular risk prediction /
[ Blakeg,J.;P.M.ridker ] / J. Inte. Medicine   ScienceOn