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Antioxidant Activity of Rosa rugosa  

서영완 (한국해양대학교 해양과학부)
이희정 (한국해양대학교 해양과학기술연구소)
안종웅 (한국해양대학교 해양과학부)
이범종 (인제대학교 화학과)
문성기 (경성대학교 생물학과)
Publication Information
KSBB Journal / v.19, no.1, 2004 , pp. 67-71 More about this Journal
Abstract
An antioxidant activity of Rosa rugosa extract and its solvent-partitioned fractions was determined not only by measuring lipid peroxide produced when a mouse liver homogenate was exposed to the air at 37$^{\circ}C$, using thiobarbituric acid (TBA) but also by evaluating the free radical scavenging effect against DPPH radical, authentic peroxynitrite, and 3-morpholinsydnonimine (SIN-1). All its partitioned fractions including crude extract showed potent scavenging effect against DPPH radical, peroxynitrite, and lipid peroxidation. n-BuOH fraction, in particular, was found to be the most effective in DPPH radical scavenging ability as well as inhibition against lipid peroxidation. The 15% aqueous MeOH fraction also showed a strong potency which was slightly lower than n-BuOH fraction. Based on these results, we suggest that Rosa rugosa could be useful for preventing an oxidative damage.
Keywords
Rosa rugosa; peroxynitrite; DPPH; radical scavenging activity; lipid peroxidation;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
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