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Hydrogel Synthesis using Glycosyl Methacrylate and Acrylate: 1. A Study on Chemo-Enzymatic Synthesis of Sorbitan Acrylate  

박돈희 (전남대학교 응용화학공학부, 생물산업기술연구소, 촉매연구소)
임근길 (산업안전공단)
정귀택 (전남대학교 응용화학공학부)
변기영 (전남대학교 응용화학공학부)
김인흥 (㈜대한진공)
이광연 (동아인재대학 안경광학과)
김해성 (명지대학교 화학공학과)
Publication Information
KSBB Journal / v.18, no.3, 2003 , pp. 222-228 More about this Journal
Abstract
This study was performed to research a chemo-enzymatic synthesis of sorbitan acrylate. It w as firstly to determine the optimum conditions for D-sorbitol cyclic reaction in the presence of p-toluenesulfonic acid (p-TSA) as catalyst material. It was secondly to find the optimum conditions for sorbitan acrylate synthesis using immobilized lipase Novozym 435 in t-butanol from its materials. The maximum yield of 1,4-sorbitan synthesis were obtained approximately 90% (w/w) at 13$0^{\circ}C$ and 200 mmHg vacuum pressure with 1% (w/w) p-TSA after 150 min reactin time on our experimental system. The product from optimum condition was less color than those obtained at higher temperatures and minimized byproduct and unreacted D-sorbitol. Sorbitan acrylate was synthesized to around 63.5% conversion of 1,4-sorbitan. The experimental optimum condition was found at 5$0^{\circ}C$, atmospheric pressure, 3% (w/v) Novozym 435, 50 g/L 1,4-sorbitan of initial reactant concentration, and 1:3 molar ratio of 1,4-sorbitan to acrylic acid.
Keywords
Sorbitan; chemo-enzymatic synthesis; sorbitan acrylate;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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