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Screening of the Immuno-stimulatory Activity of the Marine Alga Chlorella capsulate  

이현수 (강원대학교 바이오산업공학부)
이서호 (강원대학교 바이오산업공학부)
문형철 (강원대학교 바이오산업공학부)
이현용 (강원대학교 바이오산업공학부)
Publication Information
KSBB Journal / v.18, no.1, 2003 , pp. 19-24 More about this Journal
Abstract
A purified substance was separated from marine alga, Chlorella capsulate. Immuno-stimulatory activity was measured by observing the growth of human immune T and B cells. The growth of human T and B cells was enhanced by up to about 1.4 times by adding the fraction from C. capsulata, compared with commercially available CGF extracts from the fresh water alga, C. vulgaris. The secretion of TNF-a and IL-6 was also enhanced up to about 1.5 times by adding the separated fraction. Adding 0.4 g/L of the extract increased the production of nitric oxide from macrophages by 1.6 fold. 50% of the AGS cell growth was inhibited by adding 0.4 g/L of the water extracted sample.
Keywords
Chlorella capsulata; human T and B cells; macrophage; immune-stimulatory activity;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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