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http://dx.doi.org/10.5322/JES.2003.12.6.599

Effects of Houttuynia Cordata thunb on Antioxidative Activity against TCDD Damage  

하배진 (신라대학교 공과대학)
Publication Information
Journal of Environmental Science International / v.12, no.6, 2003 , pp. 599-603 More about this Journal
Abstract
This study investigated the effects of Houttuynia Cordata thunb(HCT) administration on the biochemical parameters of function in liver of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) treated rats. Houttuynia Cordata thunb (200mg/kg) was administeres into rats intraperitoneally for four weeks , seven days after the injection of TCDD(1$\mu\textrm{g}$/kg). We examined the antioxidative enzymatic activity by measuring the level of AST, ALT , SOD and Catalase in serum and liver tissue of rats. HCT group showed 49% of inhibitive effect in AST activity compared to TANO group. ALT level of HCT group was decreased to the level of NO group. SOD and Catalase in TANO group were lower than in NO group, but SOD and Catalase in HCT group were increased by 46％ and by 50％ respectively compared to TANO group.
Keywords
TCDD; Houttuynia Cordata thunb; Antioxidative enzyme; Hepatotoxicity;
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