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http://dx.doi.org/10.5292/jkbjts.2013.19.2.50

Analysis for Usefulness of Arterial Embolization on Sacral and Pelvic Giant Cell Tumors  

Kim, Seung Hyun (Department of Orthopedic Surgery, Yonsei University College of Medicine)
Yoon, Gil Sung (Department of Orthopedic Surgery, Yonsei University College of Medicine)
Cho, Yong Jin (Department of Orthopedic Surgery, Yonsei University College of Medicine)
Shin, Kyoo-Ho (Department of Orthopedic Surgery, Yonsei University College of Medicine)
Suh, Jin-Suck (Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine)
Yang, Woo-Ick (Department of Pathology, Yonsei University College of Medicine)
Publication Information
The Journal of the Korean bone and joint tumor society / v.19, no.2, 2013 , pp. 50-55 More about this Journal
Abstract
Purpose: The purpose of this study is to determine the usefulness of arterial embolization on sacral and pelvic giant cell tumor (GCT). Materials and Methods: We retrospectively reviewed the medical records of 9 patients who had undergone serial arterial embolization between December 1996 and May 2008. We analyzed the clinical outcomes and therapeutic responsiveness of arterial embolization on sacral and pelvic GCT. Results: Six of 9 cases showed progression of disease (PD) status, even if 5 cases showed PD status despite of additional treatments including surgery and radiation, implying that serial arterial embolization on sacral and pelvic GCT is not effective. Three of 9 cases showed stable disease (SD) or continuous disease free (CDF) status and we analyzed associated factors with these good responses for embolization by ${\chi}^2$ test. The number of feeding vessels under six (p=0.048) and the number of collateral arterial supply under three (p=0.048) in the first angiogram showed significant relationships with good response for embolization, while remaining tumor staining by contrast after the first embolization and repeated embolization times were not significant. Conclusion: Although serial arterial embolization is not an effective modality on sacral and pelvic giant cell tumors, it may be a pilot modality under narrow indication of tumors with poor vascularity at first angiogram.
Keywords
sacrum; pelvic bone; giant cell tumor; arterial embolization;
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