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http://dx.doi.org/10.5292/jkbjts.2011.17.1.17

Chondrosarcoma Arising from Benign Bone Tumor due to Malignant Transformation  

Cho, Wan-Hyeong (Department of Orthopedic Surgery, Korea Cancer Center Hospital)
Song, Won-Seok (Department of Orthopedic Surgery, Korea Cancer Center Hospital)
Kong, Chang-Bae (Department of Orthopedic Surgery, Korea Cancer Center Hospital)
Hong, Yun-Suk (Department of Orthopedic Surgery, Korea Cancer Center Hospital)
Lee, Jung-Dong (Department of Orthopedic Surgery, Korea Cancer Center Hospital)
Jeon, Dae-Geun (Department of Orthopedic Surgery, Korea Cancer Center Hospital)
Publication Information
The Journal of the Korean bone and joint tumor society / v.17, no.1, 2011 , pp. 17-22 More about this Journal
Abstract
Purpose: We analyzed the oncological outcome and prognostic factor of the chondrosarcoma arising from benign bone tumor due to malignant transformation. Materials and Methods: From April 1986 to April 2009, 18 cases were considered eligible. We analyzed retrospectively the patient's characteristics and prognostic factors that affect to the local recurrence and distant metastasis. Results: As classified by primary benign bone tumor, 4 cases were solitary osteochondroma, 11 cases were multiple osteochondromatosis and 3 cases were multiple enchondromatosis. The mean follow-up period was 85 months. The 5-year disease free survival rate of 18 patients was 85.9%. Their overall MSTS score was 25.2 (84%). There were local recurrence in 3 cases and no distant metastasis. We found that tumor location and surgical margin affected to the prognosis significantly. Conclusion: In secondary chondrosarcoma patients, the prognosis was good relatively and tumor location and surgical margin are important prognosis factor.
Keywords
chondrosarcoma; maliganant transformation; prognostic factor;
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