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http://dx.doi.org/10.12655/KADH.2018.14.2.92

VALPROATE-INDUCED GINGIVAL OVERGROWTH : A CASE REPORT  

Song, Jihyeo (Department of Pediatric Dentistry, College of Dentistry, Yonsei University)
Lee, Koeun (Department of Pediatric Dentistry, College of Dentistry, Yonsei University)
Shin, Minkyung (Department of Pediatric Dentistry, College of Dentistry, Yonsei University)
Kim, Seong-Oh (Department of Pediatric Dentistry, College of Dentistry, Yonsei University)
Choi, Byungjai (Department of Pediatric Dentistry, College of Dentistry, Yonsei University)
Choi, Hyung-Jun (Department of Pediatric Dentistry, College of Dentistry, Yonsei University)
Publication Information
The Journal of Korea Assosiation for Disability and Oral Health / v.14, no.2, 2018 , pp. 92-96 More about this Journal
Abstract
Drug-induced gingival overgrowth is an abnormal increase of gingival tissues caused as a side effect of systemic medication. This report presents a severe case of valproate-induced gingival overgrowth combined with ulcerative and hemorrhagic lesions in a patient with Lennox-Gastaut syndrome. Considering the patient's limited cooperative ability, gingivectomy and excisional biopsy under general anesthesia were performed. The lesions were successfully treated without recurrence. When gingival enlargement does not subside with nonsurgical treatments, surgical procedure and excisional biopsy are to be performed. Postoperative management of oral hygiene is critical to prevent recurrence.
Keywords
Drug-induced gingival overgrowth; Valproate; Lennox-Gastaut syndrome; Gingivectomy;
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