Browse > Article
http://dx.doi.org/10.12655/jkdoh.2013.9.1.46

CARIES TREATMENT OF A MIDAZOLAM-PREMEDICATED PATIENT WITH DEVELOPMENTAL DISORDERS : A CASE REPORT  

Kim, Hyo-Eun (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Shin, Teo-Jeon (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Kim, Young-Jae (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Kim, Jung-Wook (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Jang, Ki-Taeg (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Lee, Sang-Hoon (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Kim, Chong-Chul (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Hyun, Hong-Keun (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Publication Information
The Journal of Korea Assosiation for Disability and Oral Health / v.9, no.1, 2013 , pp. 46-50 More about this Journal
Abstract
Developmental disorders are a group of psychiatric conditions originating in childhood that involve serious impairments in different areas. These disorders comprise language disorders, learning disorders, motor disorders and autism spectrum disorders. Midazolam is a short-acting drug in the benzodiazepine class developed by Hoffmann-La Roche in the 1970s. The drug is used for treatment of acute seizures, moderate to severe insomnia, and for inducing sedation and amnesia before medical procedures. It possesses profoundly potent anxiolytic, amnestic, hypnotic, anticonvulsant, skeletal muscle relaxant, and sedative properties. The anterograde amnesia property of midazolam is useful for premedication before surgery to inhibit unpleasant memories. This article presents a case report including caries treatment of a 8-year-old male patient with developmental disorders using oral midazolam premedication as an alternative method of behavior management prior to general anesthesia.
Keywords
Developmental disorders; Midazolam; Premedication; General anesthesia;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Feld LH, Negus JB, White PF: Oral midazolam preanesthetic medication in pediatric outpatients. Anesthesiology, 73(5):831-834, 1990.   DOI   ScienceOn
2 Walker SE, Grad HA, Haas DA, Mayer A: Stability of parenteral midazolam in an oral formulation. Anesth Prog, 44(1):17-22, 1997.
3 Barash PG, Cullen BF, Stoelting RK, Cahalan M, Stock MC: Clinical Anesthesia, 6th Edition. Lippincott Williams Wilkins. p. 588, 2009.
4 Khail SN, Vije HN, Kee SS, Farag A, Hanna E, Chuang AZ: A paediatric trial comparing midazolam/Syrpalta mixture with premixed midazolam syrup (Roche). Paediatr Anaesth, 13(3):205-209, 2003.   DOI   ScienceOn
5 Shrestha S, Shrestha BR: Oral administration of intravenous solution of midazolam mixed in syrup of paracetamol is an effective way of premedicating children undergoing surgery under general anaesthesia. Kathmandu Univ Med J, 5(4):449-455, 2007.
6 Yuen VM, Hui TW, Irwin MG, Yuen MK: A comparison of intranasal dexmedetomidine and oral midazolam for premedication in pediatric anesthesia: a double-blinded randomized controlled trial. Anesth Analg, 106(6):1715-1721, 2008.   DOI   ScienceOn
7 Chernik DA, Gillings D, Laine H, Hendler J, Silver JM, Davidson AB, Schwam EM, Siegel JL: Validity and reliability of the Observer's Assessment of Alertness/Sedation Scale: study with intravenous midazolam. Clin Psychopharmacol, 10(4):244-251, 1990.
8 Jackson K, Winkley R, Faust OA, Cermak EG, Burtt MM: Behavior changes indicating emotional trauma in tonsillectomized children. Pediatrics, 12(1):23-27, 1953.
9 Eckenhoff JE: Relationship of anesthesia to postoperative personality changes in children. AMA Am J Dis Child, 86(5):587-591, 1953.
10 Vernon DT, Schulman JL, Foley JM: Changes in children's behavior after hospitalization. Am J Dis Child, 111(6):581-593, 1966.   DOI
11 Brzustowicz RM, Nelson DA, Betts EK, Rosenberry KR, Swedlow DB: Efficacy of oral premedication for pediatric outpatient surgery. Anesthesiology, 60(5):475-477, 1984.   DOI   ScienceOn
12 Mandrioli R, Mercolini L, Raggi MA: Benzodiazepine metabolism: an analytical perspective. Curr Drug Metab, 9(8):827-844, 2008.   DOI   ScienceOn
13 Olkkola, KT.; Ahonen J: Midazolam and other benzodiazepines. Handb Exp Pharmacol, (182): 335-60, 2008.
14 Dundee JW, Halliday NJ, Harper KW, Brogden RN: Midazolam. A review of its pharmacological properties and therapeutic use. Drugs, 28(6):519-543, 1984.   DOI   ScienceOn
15 Rutter M, Bishop DVM, Pine DS, Scott S, Stevenson J, Taylor E, Thapar A : Rutter's Child and Adolescent Psychiatry, 5th Edition. Blackwell Publishing Ltd. pp. 32-33, 2009.
16 Thikkurissy S, Lal S: Oral health burden in children with systemic diseases. Dent Clin North Am, 53(2):351-357, 2009.   DOI   ScienceOn