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http://dx.doi.org/10.22722/KJPM.2015.23.2.114

Risk Factors for Depression of Patients with Tuberculosis in Tuberculosis Specialty Hospital  

Wang, Jung-Hyun (Department of Psychiatry, Gyeongsang National University Hospital)
Park, Chul-Soo (Department of Psychiatry, Gyeongsang National University Hospital)
Kim, Bong-Jo (Department of Psychiatry, Gyeongsang National University Hospital)
Lee, Cheol-Soon (Department of Psychiatry, Gyeongsang National University Hospital)
Cha, Boseok (Department of Psychiatry, Gyeongsang National University Hospital)
Lee, So-Jin (Department of Psychiatry, Gyeongsang National University Hospital)
Lee, Dongyun (Department of Psychiatry, Gyeongsang National University Hospital)
Seo, Ji-Yeong (Department of Psychiatry, Gyeongsang National University Hospital)
Ahn, InYoung (Department of Neuropsychiatry, Seoul National University Hospital)
Baek, Jong Chul (Department of Obstetrics and Gynecology, Gyeongsang National University Hospital)
Kang, Hyung Seok (Masan National Tuberculosis Hospital)
Moon, Sung Ho (Department of Thoracic and Cardiovascular Surgery, Gimhae Jungang Hospital)
Publication Information
Korean Journal of Psychosomatic Medicine / v.23, no.2, 2015 , pp. 114-120 More about this Journal
Abstract
Objectives : This study aimed to investigate the risk factors of depression for patients with tuberculosis(TB). Methods : A total of 57 patients with TB were recruited. All participants completed the Becks Depression Inventory-II for evaluating depressive symptoms. The risk factor for depression was analyzed by binary logistic regression analysis. Nomogram was performed for probability of depression. Results : Low body mass index(BMI, OR 0.801, 95% CI 0.65, 0.98), interruption of treatment for TB(OR 5.908, 95% CI 1.19, 29.41), past history of depression(OR 24.653, 95% CI 1.99, 308.44) were associated with increased risk for depression. The calibration curve for predicting probability of survival showed a good agreement between the nomogram and actual observation(Original C-index=0.789, bias corrected C-index=0.754). Conclusions : The result of the present study indicate that low BMI, interruption of treatment for TB, and past history of depression were risk factors for depression in patients with TB. The psychiatric intervention may be needed to prevent depression if the patients with TB have risk factor during treatment for TB.
Keywords
Tuberculosis; Depression; Risk factors;
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  • Reference
1 WHO. Global tuberculosis report;2014.
2 보건복지가족부. 규제영향분석서;2007.
3 Snider DE Jr, Roper WL. The new tuberculosis. N Engl J Med 1992;326:703-705.   DOI
4 Coker R, Thomas M, Lock K, Martin R. Detention and the evolving threat of tuberculosis: evidence, ethics, and law. J Law Med Ethics 2007;35:609-615.   DOI
5 Ugarte-Gil C, Ruiz P, Zamudio C, Canaza L, Otero L, Kruger H, Seas C. Association of Major Depressive Episode with Negative Outcomes of Tuberculosis Treatment. PLoS ONE 2013; 8:e69514.   DOI
6 Shen T-C, Wang C-Y, Lin C-L, Liao W-C, Chen C-H, Tu C-Y, Hsia T-C, Shih C-M, Hsu W-H, Chung C-J. People with tuberculosis are associated with a subsequent risk of depression. Eur J Intern Med 2014;25:936-940.   DOI
7 Prince M PV, Saxena S, Maj M, Maselko J, Phillips MR, Rahman A. No health without mental health. Lancet 2007;370:859-877.   DOI
8 송광례. 결핵전문병원 폐결핵환자의 삶의 질에 관한 연구. 마산: 경남대학교 행정대학원;2009.
9 Erdem M, Tasci N. Determination of self-esteem levels of patients with tuberculosis. Tuberk Toraks 2003;51:171-176.
10 Covino NA, Dirks JF, Fisch RI, Seidel JV. Characteristics of depression of chronically ill medical patients. An elaboration of personality styles. Psychother Psychosom 1983;39:10-22.   DOI
11 Duarte EC, Bierrenbach AL, da Silva JB, Tauil PL, de Fatima Duarte E. Factors associated with deaths among pulmonary tuberculosis patients: a case-control study with secondary data. J Epidemiol Community Health 2009;63:233-238.   DOI
12 Sweetland A, Oquendo M, Wickramaratne P, Weissman M, Wainberg M. Depression: a silent driver of the global tuberculosis epidemic. World Psychiatry 2014;13:325-326.   DOI
13 박정웅. 만성 질환자의 우울 정도에 따른 약물 복용 순응도. 대구: 계명대학교 대학원;2006.
14 Issa BA, Yussuf AD, Kuranga SI. Depression comorbidity among patients with tuberculosis in a university teaching hospital outpatient clinic in Nigeria. Ment Health Fam Med 2009; 6:133-138.
15 Bilyk MA, Dubchik G. Astheno-depressive syndrome in patients with pulmonary tuberculosis after administration of protionamide. Klin Med Mosk 1976;54:111-112.
16 Masumoto S, Yamamoto T, Ohkado A, Yoshimatsu S, Querri AG, Kamiya Y. Prevalence and associated factors of depressive state among pulmonary tuberculosis patients in Manila, The Philippines. Int J Tuberc Lung Dis 2014;18:174-179.   DOI
17 Peltzer K, Naidoo P, Matseke G, Louw J, McHunu G, Tutshana B. Prevalence of psychological distress and associated factors in tuberculosis patients in public primary care clinics in South Africa. BMC Psychiatry 2012;12:89-89.   DOI
18 Yew WW, Wong CF, Wong PC, Lee J, Chau CH. Adverse neurological reactions in patients with multidrug-resistant pulmonary tuberculosis after coadministration of cycloserine and ofloxacin. Clin Infect Dis 1993;17:288-289.   DOI
19 Dozois D DK, Ahnberg J. A Psychometric Evaluation of the Beck Depression Inventory-II. Psychol Assess 1998;10:83-89.   DOI
20 Hyung-Mo S, Jung-Bum K, Young-Nam P, Dai-Seok B, Sun- Hee L, Hyun-Nie A. 한국어판 백 우물 설문지 2판의 신뢰도 및 타당도 연구. J Korean Soc Biol Ther Psychiatry 2008;14:201-212.
21 Balachandran VP, Gonen M, Smith JJ, DeMatteo RP. Nomograms in oncology: more than meets the eye. Lancet 2015;16: 173-180.   DOI
22 Rim TH, Lee CS, Lee SC, Chung B, Kim SS. Influence of visual acuity on suicidal ideation, suicide attempts and depression in South Korea. Br J Ophthalmol 2015;99:1112-1119.   DOI
23 Harrell J, Frank E. Regression Modeling Strategies With Applications to Linear Models, Logistic Regression, and Survival Analysis. New York: Springer;2001.
24 McMurray D, Cegielski J. The influence of nutrition on the risk and outcomes of tuberculosis. Academy of Sciences of South Africa Consensus Panel on Nutrition, HIV/AIDS, and TB HIV/AIDS, TB, and nutrition: scientific inquiry into the nutritional influences on human immunity with special reference to HIV infection and active TB in South Africa Pretoria: Academy of Sciences of South Africa;2007.
25 Frank E. Harrell J. Regression Modeling Strategies With Applications to Linear Models, Logistic and Ordinal Regression, and Survival Analysis. New York: Springer;2015.
26 WHO. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004;363:157-163.   DOI
27 de Wit LM, van Straten A, van Herten M, Penninx BWJH, Cuijpers P. Depression and body mass index, a u-shaped association. BMC Public Health 2009;9:14-14.   DOI
28 Miller AH, Maletic V, Raison CL. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol Psychiatry 2009;65:732-741.   DOI
29 Baumeister H HM. Mental disorders in patients with obesity in comparison with healthy probants. Int J Obesity 2007;31:1155-1164.   DOI
30 Dorhoi A, Kaufmann SHE. Perspectives on host adaptation in response to Mycobacterium tuberculosis: Modulation of inflammation. Semin Immunol 2014;26:533-542.   DOI
31 Pachi A, Bratis D, Moussas G, Tselebis A. Psychiatric morbidity and other factors affecting treatment adherence in pulmonary tuberculosis patients. Tuberc Res Treat 2013;2013:489865.
32 강초롱. 일부 결핵 입원환자의 우울증 관련 요인. 광주: 조선대학교 보건대학원;2012.
33 Vega P, Sweetland A, Acha J, Castillo H, Guerra D, Smith Fawzi MC, Shin S. Psychiatric issues in the management of patients with multidrug-resistant tuberculosis. Int J of Tuberc Lung Dis 2004;8:749-759.
34 Husain MO, Dearman SP, Chaudhry IB, Rizvi N, Waheed W. The relationship between anxiety, depression and illness perception in tberculosis patients in Pakistan. Clin Pract Epidemiol Ment Health 2008;4:4.   DOI
35 Nel A, Kagee A. Common mental health problems and antiretroviral therapy adherence. AIDS Care 2011;23:1360-1365.   DOI
36 Park SK, Lee WC, Lee DH, Mitnick CD, Han L, Seung KJ. Self-administered, standardized regimens for multidrug-resistant tuberculosis in South Korea. Int J Tuberc Lung Dis 2004; 8:361-368.
37 Jeon CY, Hwang SH, Min JH, Prevots DR, Goldfeder LC, Lee H, Eum SY, Jeon DS, Kang HS, Kim JH, Kim BJ, Kim DY, Holland SM, Park SK, Cho SN, Barry CE, 3rd, Via LE. Extensively drug-resistant tuberculosis in South Korea: risk factors and treatment outcomes among patients at a tertiary referral hospital. Clin Infect Dis 2008;46:42-49.   DOI
38 Kruijshaar ME, Barendregt J, Vos T, De Graaf R, Spijker J, Andrews G. Lifetime prevalence estimates of major depression: An indirect estimation method and a quantification of recall bias. Eur J Epidemiol 2005;20:103-111.   DOI
39 Eaton WW, Shao H, Nestadt G, Lee BH, Bienvenu OJ, Zandi P. Population-based study of first onset and chronicity in major depressive disorder. Arch Gen Psychiatry 2008;65:513-520.   DOI
40 Moffitt TE, Caspi A, Taylor A, Kokaua J, Milne BJ, Polanczyk G, Poulton R. How common are common mental disorders? Evidence that lifetime prevalence rates are doubled by prospective versus retrospective ascertainment. Psychol Med 2010;40:899-909.   DOI
41 Solomon DA, Keller MB, Leon AC, Mueller TI, Lavori PW, Shea MT, Coryell W, Warshaw M, Turvey C, Maser JD, Endicott J. Multiple recurrences of major depressive disorder. Am J Psychiatry 2000;157:229-233.   DOI
42 Chapman DP, Whitfield CL, Felitti VJ, Dube SR, Edwards VJ, Anda RF. Adverse childhood experiences and the risk of depressive disorders in adulthood. J Affect Disord 2004;82:217-225.   DOI
43 Dowlati Y, Herrmann N, Swardfager W, Liu H, Sham L, Reim EK, Lanctot KL. A Meta-Analysis of Cytokines in Major Depression. Biol Psychiatry 2010;67:446-457.   DOI
44 Rubel AJ, Garro LC. Social and cultural factors in the successful control of tuberculosis. Public Health Rep 1992;107:626-636.
45 Kiecolt-Glaser JK, Glaser R. Depression and immune function: central pathways to morbidity and mortality. J Psychosom Res 2002;53:873-876.   DOI
46 Mikkelsen RL, Middelboe T, Pisinger C, Stage KB. Anxiety and depression in patients with chronic obstructive pulmonary disease(COPD). A review. Nord J Psychiatry 2004;58:65-70.   DOI
47 Reiche EM, Nunes SO, Morimoto HK. Stress, depression, the immune system, and cancer. Lancet Oncol 2004;5:617-625.   DOI
48 Trenton AJ, Currier GW. Treatment of Comorbid Tuberculosis and Depression. Prim Care Companion J Clin Psychiatry 2001;3: 236-243.   DOI
49 Acha J, Sweetland A, Guerra D, Chalco K, Castillo H, Palacios E. Psychosocial support groups for patients with multidrug-resistant tuberculosis: Five years of experience. Glob Public Health 2007;2:404-417.   DOI
50 Janmeja AK, Das SK, Bhargava R, Chavan BS. Psychotherapy improves compliance with tuberculosis treatment. Respiration 2005;72:375-380.   DOI