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http://dx.doi.org/10.7852/jses.2013.51.2.147

Comparison of fibrinolytic activity from Korean indigenous insects  

Kim, Hyunae (National Academy of Agricultural Science, RDA)
Lee, Sang Han (School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University)
Choi, Youngcheol (National Academy of Agricultural Science, RDA)
Park, Kwanho (National Academy of Agricultural Science, RDA)
Hwang, Jaesam (National Academy of Agricultural Science, RDA)
Kim, Namjung (National Academy of Agricultural Science, RDA)
Nam, Sunghee (National Academy of Agricultural Science, RDA)
Publication Information
Journal of Sericultural and Entomological Science / v.51, no.2, 2013 , pp. 147-152 More about this Journal
Abstract
The fibrinolytic activity of aqueous extracts from Korean indigenous insects were studied. Fibrinolytic activity of aqueous extract from 5 insects (larva and adult parts of Meloimorpha japonica, Allomyrina dichotoma, Cetonia pilifera, Apis mellifera) showed 2.7-fold potent than that of plasmin used as a positive control. In addition, the fibrinolytic activity was observed through the degradation products by SDS-PAGE. The extracts efficiently hydrolyzed ${\alpha}-$, ${\beta}-$ and ${\gamma}$ chains of human fibrinogen. This study suggested that aqueous extracts from Korean indigenous insects have potential in developing a useful source of antithrombosis agent(s).
Keywords
Antithrombosis; Indigenous insects; Fibrinolytic activity;
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Times Cited By KSCI : 3  (Citation Analysis)
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