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http://dx.doi.org/10.7732/kjpr.2022.35.2.385

Anti-Obesity Effect of Pinus densiflora Leaf Extracts  

Choi, Min Yeong (Department of Medicinal Plant Resources, Andong National University)
Shin, Byel (PINOGEN Co., Ltd)
Yu, Ju Hyeong (Department of Medicinal Plant Resources, Andong National University)
Yeo, Joo Ho (Department of Medicinal Plant Resources, Andong National University)
Lee, Jae Won (Department of Medicinal Plant Resources, Andong National University)
Geum, Na Gyeong (Department of Medicinal Plant Resources, Andong National University)
An, Mi-Yun (National Forest Seed and Variety Center)
Jeong, Jin Boo (Department of Medicinal Plant Resources, Andong National University)
Publication Information
Korean Journal of Plant Resources / v.35, no.2, 2022 , pp. 385-389 More about this Journal
Abstract
In this study, we measured the inhibitory activity of Pinus densiflora leaf (PDL) against excessive lipid accumulation in mouse preadipocyte, 3T3-L1 cells to investigate whether PDL exerts anti-obesity activity. Lipid accumulation and the protein level were measured using Oil red O staining assay and Western blot analysis, respectively. We observed that PDL inhibited excessive lipid accumulation and decreased the expression of CEBPα, PPARγ and perilipin-1 related to lipid accumulation in 3T3-L1 cells. Therefore, considering these results, PDL can be used as a potential agent for anti-obesity.
Keywords
Anti-obesity activity; Adipocytes; Pinus densiflora; 3T3-L1 cells;
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