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http://dx.doi.org/10.7732/kjpr.2020.33.3.163

Improving Effects of Brassica oleracea L. var. italica Sprout Extract on Alcoholic Liver Dysfunction  

Kim, Min Jeong (Korea Food Research Institute)
Yang, Hye Jeong (Korea Food Research Institute)
Lee, Hak Yong (INVIVO Co. Ltd.)
Park, Young Mi (INVIVO Co. Ltd.)
Shin, Dong Yeop (INVIVO Co. Ltd.)
Lee, Yang Hee (INVIVO Co. Ltd.)
Kang, Yang Gyu (INVIVO Co. Ltd.)
Kim, Tae Su (Anydoctor HealthCare Co. Ltd.)
Lee, Sung Pyo (Anydoctor HealthCare Co. Ltd.)
Park, Kwang-Hyun (Department of Emergency Medical Rescue and Department of Oriental Pharmaceuticals Development, Nambu University)
Publication Information
Korean Journal of Plant Resources / v.33, no.3, 2020 , pp. 163-169 More about this Journal
Abstract
Alcoholic fatty liver disorder has become a frequent health concern worldwide. To investigate the effects of Brassica oleracea (B. oleracea) sprout extract (BOE), the present study was designed with alcoholic fatty liver in the rat. Initially, the effects of BOE on liver parameters were examined. Male rats were divided into five groups. The normal control group was fed the normal diet, and the BOE group was fed the high fat diet and ethanol with/without BOE for 4 weeks. After 4 weeks feeding period, rats were sacrificed and their livers and blood were used for fatty liver-related biomarkers analyses. As a result, BOE ameliorated fatty liver-related enzymes profiles in liver tissues and also reduced blood alcohol concentration in rat model. We demonstrated that BOE protected the high fat diet and alcohol-induced fatty liver in rat model. Furthermore, BOE increased detoxificative abilities against alcohol.
Keywords
Alcoholic liver dysfunction; Brassica oleracea sprout extract; Fatty liver; High fat diet;
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