In Vitro Cytotoxicity against Human Cancer Cell and 3T3-L1 Cell, Total Polyphenol Content and DPPH Radical Scavenging of Codonopsis lanceolata according to the Concentration of Ethanol Solvent |
Boo, Hee-Ock
(WELLPHYTO Co. Ltd., BI Center, GIST)
Park, Jeong-Hun (WELLPHYTO Co. Ltd., BI Center, GIST) Lee, Moon-Soon (Department of Industrial Plant Science & Technology, Chungbuk National University) Kwon, Soo-Jeong (Faculty of Food Nutrition and Cookery, Woosong Information College) Kim, Hag-Hyun (Faculty of Food Nutrition and Cookery, Woosong Information College) |
1 | Yokozawa, T., C. P. Chen, E. Dong, T. Tanaka, G.I. Nonaka and I. Nishioka. 1998. Study on the inhibitory effect of tannins and flavonoids against the 1,1-diphenyl-2-picrylhydrazyl radical. Biochem. Phamacol. 56:213-222. DOI |
2 | Zhishen, J., T. Mengcheng and W. Jianming. 1999. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem. 64:555-559. DOI |
3 | Zhou, K. and L. Yu. 2006. Total phenolic contents and antioxidant properties of commonly consumed vegetables grown in Colorado. LWT . 39:1155-1162. DOI |
4 | Zhu, N., M. Wang, G.J. Wei, J.K. Lin, C.S. Yang and C.T. Ho. 2001. Identification of reaction products of (-)-epigallocatechin, (-)-epigallocatechin gallate and pyrogallol with 2,2-diphenyl-1-picrylhydrazyl radical. Food Chem. 73:345-349. DOI |
5 | Boo, H.O., J.H. Shin, J.S. Shin, E.S. Choung, M.A. Bang, K.M. Choi and W.S. Song. 2012. Assessment on antioxidant potential and enzyme activity of some economic resource plants. Korean J. Plant Res. 25(3):349-356. DOI |
6 | Boo, H.O., J.H. Park, H.G. Kim, H.H. Kim, S.J. Kwon, D.Y. Seo and M.S. Lee. 2016. Immune cells activity, nitrite scanvenging and ABTS radical scavenging activities of Codonopsis lanceolata ethanol extracts from districts in Korea. Korean J. Plant Res. 29(3):289-296. DOI |
7 | Ejaz, A., D. Wu, P. Kwan and M. Meydani. 2009. Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice. The Journal of Nutririon(JN). 139(5):919-925. |
8 | Brand-Williams, W., M.E. Cuvelier and C. Berset. 1995. Use of a free radical method to evaluate antioxidant activity. Food Sci. Tech. 28:25-30. |
9 | Cao, H., M.M. Polansky and R.A. Anderson. 2007. Cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3-L1 adipocytes. Arch Biochem Biophys. 459(2):214-222. DOI |
10 | Cuyacot, A.R., J.J.M. Mahilum and M.R.S.B. Madamba. 2014. Cytotoxicity potentials of some medicinal plants in Mindanao, Philippines. Pelagia Research Library 4(1):81-89. |
11 | Fu, X.J., H.B. Liu, P. Wang and H.S. Guan. 2009. A study on the antioxidant activity and tissues selective inhibition of lipid peroxidation by saponins from the roots of Platycodon grandiflorum. Am. J. Chin. Med. 37(5):967-975. DOI |
12 | Guizani, N., M.I. Waly, V. Singh and M.S. Rahman. 2013. Nabag (Zizyphus spina-christi) extract prevents aberrant crypt foci development in colons of azoxymethane-treated rats by abrogating oxidative stress and inducing apoptosis. Asian Pac J Cancer Prev. 14:5031-5035. DOI |
13 | Joh, E.H., I.A. Lee, S.J. Han, S.J. Chae and D.H. Kim. 2010. Lancemaside A ameliorates colitis by inhibiting NF-jB activation in TNBS-induced colitis mice. Int. J. Colorectal Dis. 25:545-551. DOI |
14 | Kim, C.H., B.Y. Jung, S.K. Jung, C.H. Lee, H.S. Lee, B.H. Kim and S.K. Kim. 2010. Evaluation of antioxidant activity of Platycodon grandiflorum. J. Environ. Toxicol. 25(1):85-94. |
15 | Kim, I.D., S.K. Dhungana, H.R. Kim and D.H. Shin. 2017. Quality characteristics and antioxidant potential of seeds of native Korean persimmon genotypes. Korean J. Plant Res. 30(6):670-678. DOI |
16 | Park, H.J., M.J. Kim, E. Ha and J.H. Chung. 2008. Apoptotic effect of hesperidin through caspase 3 activation in human colon cancer cells, SNU-C4. Phytomedicine 15:147-151. DOI |
17 | Kintzios, E. 2006. Terrestrial plant-derived anticancer agents and plant species used in anticancer research. Crit. Rev. Plant Sci. 25:79-113. DOI |
18 | Li, X., Y. Huang, L. Zheng, H. Liu, X. Niu, J. Huang, F. Zhao and Y. Fan. 2014. Effect of substrate stiffness on the functions of rat bone marrow and adipose tissue derived mesenchymal stem cells in vitro. J. Biomed. Mater. Res. 102(4):1092-1101. DOI |
19 | Lobo, R., K.S. Prabhu and A. Shirwaikar. 2009. Curcuma zedoaria Rosc. (white turmeric): a review of its chemical, pharmacological and ethnomedicinal properties. J. Pharm. Pharmacol. 61:13-21. DOI |
20 | Marja P.K., I.H. Anu, J.V. Heikki, R. Jussi-Pekka, P. Kalevi, S.K. Tytti and H. Marina. 1999. Antioxidant activity of plant extracts containing phenolic compounds. J. Agri. Food Chem. 47:3954-3962. DOI |
21 | Rahul, B.B. and K.B. Kamlesh. 2007. Pancreatic lipase inhibitors from natural sources: unexplored potential. Drug Discov. Today 12:879-889. DOI |
22 | Rice-Evans, C., N.J. Miller, G.P. Bolwell, P.M. Bramley and J.B. Pridham. 1995. The relative antioxidants activities of plant-derived polyphenolic flavonoids. Free Radic. Res. 22:375-383. DOI |
23 | Roh, C.H. and U.H. Jung. 2012. Screening of crude plant extracts with anti-obesity activity. Int. J. Mol. Sci. 13(2):1710-1719. DOI |
24 | Ryu, C.S., C.H. Kim, S.Y. Lee, K.S. Lee, K.J. Choung, G.Y. Song, B.H. Kim, S.Y. Ryu, H.S. Lee and S.K. Kim. 2012. Evaluation of the total oxidant scavenging capacity of saponins isolated from Platycodon grandiflorum. Food Chem. 132(1): 333-337. DOI |
25 | Sugihara, N., T. Arakawa, M. Ohnishi and K. Furuno. 1999. Anti and pro-oxidative effects of flavonoids on metal induced lipid hydroperoxide-dependent lipid peroxidation in cultured hepatocytes located with "- linolenic acid. Free Radic. Biol. Med. 27:1313-1323. DOI |
26 | Sanchez-Moreno, C., J.A. Larrauri and F. Saura-Calixto. 1999. Free radical scavenging capacity and inhibition of lipid oxidation of wines, grape juices and related polyphenolic constituents. Food Res. Int. 32:407-412. DOI |
27 | Shahidi, F. and P.K.J.P.D. Wanasundara. 1992. Phenolic antioxidants: criteria review. Food Science and Nutrition 32: 67-103. |
28 | Singleton, V. and J.A. Rossi. 1965. Colorimetry of total phenolics with phosphomolybdic phosphotungstic acid reagents. Am. J. Enology Vitic. 16:144-158. |
29 | Velioglu, Y.S., G. Mazza, L. Gao and B.D. Oomah. 1998. Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products. J. Agric. Food. Chem. 46: 4113-4117. DOI |
30 | Vijayarathna, S. and S. Sasidharan. 2012. Cytotoxicity of methanol extracts of Elaeis guineensis on MCF-7 and Vero cell lines. Asian Pac. J. Trop Biomed. 2(10):826-829. DOI |
31 | Wang, L., M.L. Xu, J.H.u, S.K. Rasmussen and M.H. Wang. 2011. Codonopsis lanceolata extract induces G0/G1 arrest and apoptosis in human colon tumor HT-29 cells - Involvement of ROS generation and polyamine depletion. Food Chem. Toxicol. 49:149-154. DOI |
32 | Yan-Wei, H., L. Chun-Yu, D. Chong-Min, W. Wen-Qian and G. Zhen-Lun. 2009. Induction of apoptosis in human hepa- tocarcinoma SMMC-7721 cells in vitro by flavonoids from Astragalus complanatus. J. Ethnopharmacol. 123:293-301. DOI |
![]() |