Safflower Bud Dietary Prevents Ovariectomy-induced Osteoporosis in Rats |
Choi, Joo Hee
(Department of Veterinary Physiology, Chonnam National University)
Lim, Seul Ki (Metabolism and Functionality Research Group, R&D division, World Institute of Kimchi) Jang, Ah Ra (Department of Veterinary Physiology, Chonnam National University) Nho, Jong Hyun (Department of Veterinary Physiology, Chonnam National University) Lim, Jae Oh (Department of Veterinary Physiology, Chonnam National University) Cho, Seong Kang (Department of Veterinary Physiology, Chonnam National University) Kim, Young Kuk (R&D team, Dasan Institute of Life & Science Co. Ltd.) Lee, An Chul (R&D team, Dasan Institute of Life & Science Co. Ltd.) Choi, Mi Young (R&D team, Dasan Institute of Life & Science Co. Ltd.) Boo, Young Min (Department of Herbology, Kyung Hee University) Park, Soo Hyun (Department of Veterinary Physiology, Chonnam National University) |
1 | Cauley, J.A., D.E. Thompson, K.C. Ensrud, J.C. Scott and D. Black. 2000. Risk of mortality following clinical fractures. Osteoporos. Int. 11:556-561. DOI |
2 | Brennan, O., J.S. Kuliwaba, T.C. Lee, I.H. Parkinson, N.L. Fazzalari, L.M. McNamara and F.J O'Brien. 2012. Temporal changes in bone composition, architecture, and strength following estrogen deficiency in osteoporosis. Calcif. Tissue Int. 91:440-449. DOI |
3 | Bae, S.J., S.M. Shim, Y.J. Park, J.Y. Lee, E.J. Chang and S.W. Choi. 2002. Cytotoxicity of phenolic compounds isolated from seeds of safflower (Carthamus tiractorious L.) on cancer cell lines. Food Sci. Biotechnol. 11:140-146. |
4 | Alam, M.R., S.M. Kim, J.I. Lee, S.K. Chon, S.J. Choi, I.H. Choi and N.S. Kim. 2006. Effects of safflower seed oil in osteoporosis induced-ovariectomized rats. Am. J. Chin. Med. 34:601-612. DOI |
5 | Osterhoff, G., G. Diederichs, A. Tami, J. Theopold, C. Josten and P. Hepp. 2012. Influence of trabecular microstructure and cortical index on the complexity of proximal humeral fractures. Arch. Orthop. Trauma. Surg. 132(4):509-515. DOI |
6 | Kneissel., M., N.H. Luong-Nguyen, M. Baptist, R. Cortesi, S. Zumstein-Mecker, S. Kossida, T. O`Reilly, H. Lane and M. Susa. 2004. Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts. Bone 35(5):1144-1156. DOI |
7 | Lelovas, P.P., T.T. Xanthos, S.E. Thoma , G.P. Lyritis and I.A. Dontas. 2008. The laboratory rat as an animal model for osteoporosis research. Comp. Med. 58:424-430. |
8 | Kim, H.Y., C.S. Kim, G.J. Jhon, I.S. Moon, S.H. Choi, K.S. Cho, J.K. Chai and C.K. Kim. 2002. The effect of safflower seed extract on periodontal healing of 1-wall intrabony defects in beagle dogs. J. Periodontol. 73:1457-1466. DOI |
9 | Kim, H.J., D.S. Sim and E.H. Sohn. 2014. Anti-osteoporotic effects of unripe fructus of Rubus coreanus Miquel in osteoblastic and osteoclastic cells. Korean J. Plant Res. 27(6):593-600. DOI |
10 | Kalu, D.N. 1991. The ovariectomized rat model of postmenopausal bone loss. Bone Miner. 15(3):175-191. DOI |
11 | Yogesh, H.S., V.M. Chandrashekhar, H.R. Katti, S. Ganapaty, H.L. Raghavendra, G.K. Gowda and B. Goplakhrishna. 2011. Anti-osteoporotic activity of aqueous-methanol extract of Berberis aristata in ovariectomized rats. J. Ethnopharmacol. 134(2):334-338. DOI |
12 | Holzer, G., H. Noske, T. Lang, L. Holzer and U. Willinger. 2005. Soluble cathepsin K: a novel marker for the prediction of nontraumatic fractures? J. Lab. Clin. Med. 146(1):13-17. DOI |
13 | Hiramatsu, M., T. Takahashi, M. Komatsu, T. Kido and Y. Kasahara. 2009. Antioxidant and neuroprotective activities of Mogami-benibana (safflower, Carthamus tinctorius L.). Neurochem. Res. 34:795-805. DOI |
14 | Cummings, S.R. and L.J. Melton. 2002. Epidemiology and outcomes of osteoporotic fractures. Lancet 359:1761-1767. DOI |
15 | Wensel, T.M., M.M. Iranikhah and T.W. Wilborn. 2011. Effects of denosumab on bone mineral density and bone turnover in postmenopausal women. Pharmacotherapy 31(5):510-523. DOI |
16 | Seo, H.J., J.H. Kim, D.Y. Kwak, S.M. Jeon, S.K. Ku, J.H. Lee, K.D. Moon and M.S. Choi. 2000. The effects of safflower seed powder and its fraction on bone tissue in rib-fractured rats during the recovery. Korean J. Nutr. 33:441-420 (in Korean). |
17 | Rahman, M.M., G. Fernandes and P. Williams. 2014. Conjugated linoleic acid prevents ovariectomy-induced bone loss in mice by modulating both osteoclastogenesis and osteoblastogenesis. Lipids 49(3):211-24. DOI |
18 | Qin, D.W., Z. Gu, L. Dai and C. Ji. 2013. Protective effects of gallium, germanium, and strontium against ovariectomized osteoporosis in rats. Biol. Trace Elem. Res. 153(1-3):350-354. DOI |