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http://dx.doi.org/10.7732/kjpr.2012.25.5.647

Anticancer Effects of the Extracts of Oriental Melon (Cucumis melo L. var makuwa Makino) Seeds  

Kim, Jung-Hyun (Department of Horticultural Science, College of Agriculture and Life Sciences, Kyungpook National University)
Suh, Jun-Kyu (Department of Horticultural Science, College of Agriculture and Life Sciences, Kyungpook National University)
Kang, Young-Hwa (Department of Horticultural Science, College of Agriculture and Life Sciences, Kyungpook National University)
Publication Information
Korean Journal of Plant Resources / v.25, no.5, 2012 , pp. 647-651 More about this Journal
Abstract
The objective of this study was to investigate the anticancer effects of the extracts of oriental melon seeds. Various solvent extracts of oriental melon seeds were prepared and their anticancer effects were examined using in vitro MTT and CV assays. The anticancer effects of various extracts of oriental melon seeds were also examined in five human cancer cell lines including A549, AGS, HT-29, MCF-7 and HepG2. The ethanol extract of heated oriental melon seeds showed the potent cytotoxic effects especially against mouse hepatoma cell line(Hepa1c1c7), human hepatoma cell line(HepG2) and human breast cancer cell line(MCF-7). These data suggest that oriental melon seeds can be a promising anticancer agent against human liver and breast cancer.
Keywords
Oriental melon; Seeds; Cytotoxicity; Anticancer;
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Times Cited By KSCI : 9  (Citation Analysis)
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