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http://dx.doi.org/10.7732/kjpr.2012.25.5.640

Simultaneous Quantitative Determination of Flavone Glycosides in Youngia japonica by High-performance Liquid Chromatography  

Nugroho, Agung (Department of Applied Plant Sciences, Graduate School, Sangji University)
Park, Hee-Juhn (Department of Pharmaceutical Engineering, Sangji University)
Publication Information
Korean Journal of Plant Resources / v.25, no.5, 2012 , pp. 640-646 More about this Journal
Abstract
This research was attempted to determine the composition of flavone glycosides (luteolin 7-O-glucoside, luteolin 7-O-glucuronide, linarin) in addition to luteolin simultaneously in aerial part of Youngia japonica (Compositae) by high-performance liquid chromatography. The MeOH extract was further fractionated into the three parts, $CHCl_3$ fraction, EtOAc fraction and BuOH fraction, to investigate the contents of the four flavones in the three fractions. The content of luteolin 7-O-glucuronide (10.07 mg/g) was highest in the MeOH extract among those of the flavones. These four compounds were observed to be less than 1.0 mg/g in $CHCl_3$- and EtOAc fractions but relatively high in BuOH fraction.
Keywords
Youngia japonica; Compositae; Luteolin 7-O-glucuronide; High-performance liquid chromatography;
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