Bioconversion of Ginsenoside Rb1 to Compound K using Leuconostoc lactis DC201 |
Piao, Jin-Ying
(Korean Ginseng Center for Most Valuable Product and Ginseng Genetic Resource Bank, Kyung Hee University)
Kim, Yeon-Ju (Korean Ginseng Center for Most Valuable Product and Ginseng Genetic Resource Bank, Kyung Hee University) Quan, Lin-Hu (Korean Ginseng Center for Most Valuable Product and Ginseng Genetic Resource Bank, Kyung Hee University) Yang, Dong-Uk (Korean Ginseng Center for Most Valuable Product and Ginseng Genetic Resource Bank, Kyung Hee University) Min, Jin-Woo (Korean Ginseng Center for Most Valuable Product and Ginseng Genetic Resource Bank, Kyung Hee University) Son, Seon-Heui (Seoul Main Customs) Kim, Sang-Mok (Seoul Main Customs) Yang, Deok-Chun (Korean Ginseng Center for Most Valuable Product and Ginseng Genetic Resource Bank, Kyung Hee University) |
1 | Odashima S., T. Ohta, H. Kohno, T. Matsuda, I. Kitagawa, H. Abe and S. Arichi. 1985. Control of phenotypic expression of cultured B16 melanoma cells by plant glycosides. Cancer Res. 45:2781-2784. |
2 | Saha, B.C. and R.J. Bothast. 1996. Production, purification, and characterization of a highly glucose-tolerant novel -glucosidase from Candida peltata. Appl. Environ. Microbiol. 62:3165-3170. |
3 | Park, S.Y., E.A. Bae, J.H. Sung, S.K. Lee and D.H. Kim. 2001. Purification and characterization of ginsenoside -metabolizing beta-glucosidase from Fusobacterium K-60, a human intestinal anaerobic bacterium. Biosci Biotechnol Biochem. 65(5):1163-1169. DOI ScienceOn |
4 | Quan, L.H., Z.Q. Liang, H.B. Kim, S.H. Kim, S.Y. Kim, Y.D. Noh and D.C. Yang. 2008. Conversion of ginsenoside Rd to compound K by crude enzymes extracted from Lactobacillus brevis LH8. J. Ginseng Res. 32(3):226-231. DOI |
5 | Saitou, N. and M. Nei. 1987. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 4:406-425. |
6 | Shin, J.E., E.K. Park, E.J. Kim, Y.H. Hong, K.T. Lee and D.H. Kim. 2003. Cytotoxicity of compound K (IH-901) and ginsenoside , main biotransformants of ginseng saponins by bifidobacteria, against some tumor cells. J. Ginseng. Res. 27:129-134. DOI |
7 | Yang, S., Z. Jiang, Q. Yan and H. Zhu. 2008. Characterization of a thermo stable extacellular -glucosidase with activities of exoglucanase and transglycosylation from Paecilomyces thermophila. J. Agric. Food Chem. 56:602-608. DOI ScienceOn |
8 | Zhou, W., M.Q. Feng, J.Y. Li and P. Zhou. 2006. Studies on the preparation, crystal structure and bioactivity of ginsenoside compound K. J. Asian Natural Products Res. 8(6):519-527. DOI ScienceOn |
9 | Takino, Y. 1994. Studies on the pharmacodynamics of ginsenoside-, - and - in rats. YakugakuZasshi 114(8):550-564. |
10 | Thompson, J.D., T.J. Gibson, F. Plewniak, F. Jeanmougin and D.G. Higgins. 1997. The CLUSTAL_X windows interface: flexible trategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25:4876-4882. DOI |
11 | Weisburg, W.G., S.M. Barns, D.A. Pelletier and D.J. Lane. 1991. 16S ribosomal DNA amplification for phylogenetic study. J. Bacteriol. 173:697-703. DOI |
12 | Lee, S.J., J.H. Sung, S.J. Lee, C.K. Moon and B.H. Lee. 1999. Antitumor activity of a novel ginseng saponin metabolite in human pulmonary adenocarcinoma cells resistant to cisplatin. Cancer Letters 144(1):39-43. DOI ScienceOn |
13 | Chi, H. and G.E. Ji. 2005a. Transformation of ginsenosides Rb1 and Re from Panax ginseng by food microorganisms. Biotechnol Lett. 27(11):765-771. DOI ScienceOn |
14 | Chi, H., D.H. Kim and G.E. Ji. 2005b. Transformation of ginsenosides and Rc from Panax ginseng by food microorganisms. Biol. Pharm. Bull. 28(11):2102-2105. DOI ScienceOn |
15 | Karikura, M., T. Miyase, H. Tanizawa, T. Taniyama and Y. Takino. 1991. Studies on absorption, distribution, excretion and metabolism of ginseng saponins. VII. Comparison of the decomposition modes of ginsenoside- and in the digestive tract of rats. Chem. Pharm. Bull. Tokyo, Japan. 39(9):2357-2361. DOI ScienceOn |
16 | Kim, M.K., W.T. Im, H. Ohta, M. Lee and S.T. Lee. 2005. Sphingopyxis granuli sp. nov., a -glucosidase-producing bacterium in the family Sphingomonadaceae in -4 subclass of the Proteobacteria. J. Microbiol. 43:152-157. |
17 | Kim, S.D. 1989. Production of the convertible enzyme of ginsenoside by Rhizopus japonicus. Korean J. Mycology 17(1):31-34. |
18 | Hall, T.A. 1999. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp. Ser. 41:95-98. |
19 | Hasegawa, H., J.H. Sung, S. Matsumiya and M. Uchiyama. 1995. Main ginseng saponin metabolites formed by intestinal bacteria. Planta Med. 62:453-457. |
20 | Kimura, M. 1983. The Neutral Theory of Molecular Evolution. Cambridge University Press, Cambridge, UK. |