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http://dx.doi.org/10.7732/kjpr.2011.24.1.030

Antioxidative Activity and Cytotoxicity of Fermented Allium victorialis L. Extract  

Doh, Eun-Soo (Department of Oriental Pharmaceutical Science, Joongbu University)
Chang, Jun-Pok (Department of Oriental Pharmaceutical Science, Joongbu University)
Kil, Ki-Jung (Department of Oriental Pharmaceutical Science, Joongbu University)
Choi, Myung-Suk (Division of Environmental Forest Science, Gyeongsang National University)
Yang, Jae-Kyung (Division of Environmental Forest Science, Gyeongsang National University)
Yun, Chung-Weon (Department of Forest Resources, Kongju National University)
Jeong, Sun-Mi (Department of Oriental Pharmaceutical Science, Joongbu University)
Jung, Yun-Hae (Department of Oriental Pharmaceutical Science, Joongbu University)
Lee, Gun-Hee (Department of Oriental Pharmaceutical Science, Joongbu University)
Publication Information
Korean Journal of Plant Resources / v.24, no.1, 2011 , pp. 30-39 More about this Journal
Abstract
This study was conducted to investigate the antioxidative activity and cytotoxicity of fermented Allium victorialis extract. The results were as follows; The total polyphenol content of A. victorialis extract was 2.63 mg/g, and that of fermented A. victorialis extract was 1.65 mg/g which decreased a little by fermentation. The total flavonoid content of A. victorialis extract was 57.77 mg/g, and that of fermented A. victorialis extract was 62.27 mg/g, and this could increase a little from fermentation. Electron donating ability of A. victorialis extract was lower than vitamin C(97.71%), but before fermentation it was 82.29% and after fermentation it became 82.40%. Nitrite scavenging ability of A. victorialis extract before and after fermentation showed lower numerical value than that of butylated hydroxytoluene(BHT) at pH 2.5 but that of A. victorialis extract expressed higher than that of BHT. Superoxide dismutase-like activity showed relatively low level, 15%. Nitrite production increased by A. victorialis extract but was inhibited after fermentation. Methyl diamphetamine (MDA) content was inhibited with increased concentration of A. victorialis extract compared with $H_2O_2$ treatment but there was not any difference before and after fermentation. Therefore, production of lipid peroxide(LPO) was inhibited by A. victorialis extract. Cell viability of fibroblast cell was tend to slightly decrease with increased concentration of A. victorialis extract, but not different with control.
Keywords
Fermentation; Antioxidative activity; Cytotoxicity; A. victorialis;
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