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Antioxidative Effects of Phellinus linteus Extract  

Rhyu, Dong-Young (Department of Medical Plant Resources, Mokpo National University)
Kim, Min-Suk (Department of Medical Plant Resources, Mokpo National University)
Min, Oh-Jin (Department of Medical Plant Resources, Mokpo National University)
Kim, Dong-Wook (Department of Medical Plant Resources, Mokpo National University)
Publication Information
Korean Journal of Plant Resources / v.21, no.1, 2008 , pp. 91-95 More about this Journal
Abstract
Reactive oxygen species(ROS) or free radical-mediated oxidative stress plays an important role in the pathophysiologic process of disease state. This study investigated antioxidative effects of Phellinus linteus extract on the generation of 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical, superoxide anion radical(${O_2}^-$), hydroxyl radical(${\cdot}OH$), nitric oxide(NO), and peroxynitrite($ONOO^-$) radical and free radical-mediated protein oxidation under in vitro assay systems. This results showed that Phellinus linteus extract effectively inhibited the generation of free radicals in the all assay system with dose-dependent manner and also significantly reduced the protein oxidative level. Thus, the present study indicates that Phellinus linteus extract possesses a potent antioxidant activity and plays a beneficial role against free radical-induced oxidative injury.
Keywords
Antioxidant; Free radical; Oxidative stress; Phellinus linteus; Reactive oxygen species(ROS);
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Times Cited By KSCI : 2  (Citation Analysis)
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