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http://dx.doi.org/10.7736/KSPE.2016.33.1.69

Deformation Measurement of Polymer Scaffold Using Particle Image Analysis  

Kang, Min Je (Department of Mechanical Engineering, Myoungji University)
Oh, Sang Hoon (Department of Mechanical Engineering, Myoungji University)
Rhee, Kyehan (Department of Mechanical Engineering, Myoungji University)
Publication Information
Journal of the Korean Society for Precision Engineering / v.33, no.1, 2016 , pp. 69-75 More about this Journal
Abstract
Polydimethylsiloxane (PDMS) is used as a scaffold for cell culture. Because both the stress and strain acting on the substrate and the hemodynamic environment are important for studying mechano-transduction of cellular function, the traction force of the surface of a substrate has been measured using fluorescence images of particle distribution. In this study, deformation of the cross-sectional plane of a PDMS block was measured by correlating particle image distributions to validate the particle image strain measurement technique. Deformation was induced by a cone indentor and a shearing parallel plate. Measured deformations from particle image distributions were in agreement with the results of a computational structure analysis using the finite-element method. This study demonstrates that the particle image correlation method facilitates measurement of deformation of a polymer scaffold in the cross-sectional plane.
Keywords
Deformation measurement; Finite element analysis; Polymer scaffold; Particle image correlation;
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