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http://dx.doi.org/10.7736/KSPE.2012.29.9.1035

Effect of Intraoperative Deep Brain Stimulation on Viscoelastic Properties of Parkinsonian Rigidity during Surgery  

Kwon, Yu-Ri (School of Biomedical Engineering, Konkuk Univ.)
Eom, Gwang-Moon (School of Biomedical Engineering, Konkuk Univ.)
Park, Sang-Hun (School of Biomedical Engineering, Konkuk Univ.)
Kim, Ji-Won (School of Biomedical Engineering, Konkuk Univ.)
Koh, Seong-Beom (Department of Neurology, Korea Univ.)
Park, Byung-Kyu (Department of Physical Medicine and Rehabilitation, Korea Univ.)
Publication Information
Journal of the Korean Society for Precision Engineering / v.29, no.9, 2012 , pp. 1035-1040 More about this Journal
Abstract
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been found to be effective treatment of Parkinson's disease (PD). This study aims to evaluate the effect of DBS for rigidity during DBS surgery. Six Parkinsonian patients who received STN-DBS surgery participated in this study. The examiner imposed flexion and extension of a patient's wrist randomly. Resistance to passive movement was quantified by viscoelastic properties (two damping constants for each of flexion and extension phase and one spring constant throughout both phases). All Viscoelastic constants decreased by DBS (p<0.01). Specifically, reduction in damping constant during flexion ($B_f$) was greater than those of damping constant during extension ($B_e$) and of spring constant (p<0.05). $B_f$ would be appropriate for evaluation of effect of DBS for rigidity during DBS surgery.
Keywords
Parkinson's Disease; DBS; Rigidity; Viscoelasticity;
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