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http://dx.doi.org/10.7736/KSPE.2012.29.5.584

Effect of Bladder Wall Thickness Through Change of Bladder Volume and Material Properties on Detrusor activity Study  

Jun, Su-Min (Department of Mechanical Engineering, Sogang Univ.)
Lee, Moon-Kyu (Department of Mechanical Engineering, Sogang Univ.)
Choi, Bum-Kyoo (Department of Mechanical Engineering, Sogang Univ.)
Publication Information
Journal of the Korean Society for Precision Engineering / v.29, no.5, 2012 , pp. 584-590 More about this Journal
Abstract
The structural and functional disorder of a detrusor induces a bladder hypertrophy and degenerates a bladder muscle gradually by preventing normal urination. Thus, the thickness of the bladder wall has been increased in proportion to the degree of bladder outlet obstruction. In this study, the mechanical characteristics of the detrusor is analyzed for the physical properties and the thickness changes of the bladder muscle using a mathematically analytic method. In order to obtain the mechanical property of the bladder muscle, the tensile test of porcine bladder tissue is performed because its property is similar to that of human. The result of tensile test is applied to the mathematically model as Mooney Rivlin coefficients which represent the hyperelastic material. The model of the bladder is defined as the spherical shape with the initial volume of 50ml. The principal stress and strain according to the thickness are analyzed. Also, computer simulations for three types of the material property for the model of the bladder are performed based on the fact that the stiffness of the bladder is weakened as the progress of the benign prostatic hyperplasia. As a result, the principal stress is 341kPa at the initial thickness of 2.2mm, and is 249kPa at 6.5mm. As the bladder wall thickness increases, the principal stress decreases. The principal stress and strain decrease as the stiffness of the bladder decreases under the same thinkness.
Keywords
Bladder; Hyperelastic Model; Finite Element Method (FEM); Detrusor Overactivity; Bladder Wall Thickness;
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