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Fabrication and Mechanical Properties of Carbon Nanotube Probe for Ultrasmall Force Measurement in Biological Application  

Kwon, Soon-Geun (한국과학기술원 기계항공시스템학부 기계공학)
Park, Hyo-Jun (한국과학기술원 기계항공시스템학부 기계공학)
Lee, Hyung-Woo (Massachusetts Institute of Technology(MIT) 기계공학과)
Kwak, Yoon-Keun (한국과학기술원 기계항공시스템학부 기계공학)
Kim, Soo-Hyun (한국과학기술원 기계항공시스템학부 기계공학)
Publication Information
Journal of the Korean Society for Precision Engineering / v.25, no.5, 2008 , pp. 140-147 More about this Journal
Abstract
In this study, a carbon nanotube probe (CNT probe) is proposed as a mechanical force transducer for the measurement of pico-Newton (pN) order force in biological applications. In order to measure nantube's displacement in the air or liquid environment, the fabrication of a CNT probe with tip-specific loading of fluorescent dyes is performed using tip- specific functionalization of the nanotube and chemical bonding between dyes and nanotube. Also, we experimentally investigated the mechanical properties of the CNT probe using electrostatic actuation and fluorescence microscope measurement. Using fluorescence measurement of the tip deflection according to the applied voltage, we optimized the bending stiffness of the CNT probe, therefore determined the spring constant of the CNT probe. The results show that the spring constant of CNT probes is as small as 1 pN/nm and CNT probes can be used to measure pN order force.
Keywords
Carbon nanotube probe; Electrostatic actuation; Fluorescence Measurement; Spring constant; Genetic algorithm;
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