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http://dx.doi.org/10.22156/CS4SMB.2022.12.01.119

Antioxidant and Anti-inflammatory Activity of Grateloupia filicina extract  

Yu, Mi Young (Department of Biological Engineering, Konkuk University)
Lee, Sang Hyun (Department of Biological Engineering, Konkuk University)
Publication Information
Journal of Convergence for Information Technology / v.12, no.1, 2022 , pp. 119-126 More about this Journal
Abstract
In this study, the antioxidant ability, anti-inflammatory ability and whitening effect of the extracted Grateloupia filicina under optimal conditions were confirmed. The useful substances of Grateloupia filicina were extracted with various ethanol aqueous solutions to measure DPPH, ABTS, and nitrite radical elimination capabilities, and the polyphenol and flavonoid contents were analyzed. When extracted with a 20% ethanol aqueous solution, the radical elimination ability was the best, and the content of polyphenol and flavonoids was also the highest. From this, it was confirmed that the 20% ethanol aqueous solution efficiently extracted the antioxidant and anti-inflammatory substances of Grateloupia filicina. Meanwhile, the cytotoxicity and anti-inflammatory properties of the Grateloupia filicina extract were confirmed using RAW 264.7 cell lines. Grateloupia filicina extract did not show toxicity at a concentration of 200 ㎍/mL, and showed NO production inhibitory capacity of 50% or more at this concentration. As a result, it was confirmed that the Grateloupia filicina extract can be used as a functional cosmetic raw material having antioxidant and anti-inflammatory properties.
Keywords
Grateloupia filicina; Algae; Anti-oxidant; Anti-inflammatory; Skin whitenin;
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