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http://dx.doi.org/10.22156/CS4SMB.2021.11.07.264

Antioxidant and Anti-inflammatory activity of Sargassum patens extract  

Kim, Sook-hee (K-Beauty industry fusion, Konkuk Continuing Education Center, Konkuk University)
Publication Information
Journal of Convergence for Information Technology / v.11, no.7, 2021 , pp. 264-271 More about this Journal
Abstract
In this study, the antioxidant and anti-inflammatory properties of Sargassum patens extracts were identified. Antioxidant experiments included polyphenol concentration measurements, flavonoid concentration measurements, DPPH experiments, ABTS experiment NO experiments, and FRAP experiments. For polyphenols, 18.99±0.69 mg/g was shown. Flavonoids showed 11.89±1.16 mg/g. The DPPH experiment showed an antioxidant function of 19.78 mg ascorbic acid/g extract, the ABTS experiment showed an antioxidant function of 63.64 mg ascorbic acid/g extract, and the NO experiment showed an antioxidant function of 7.966 mg ascorbic acid/g extract. In FRAP, 1 mg of the moxibustion extract showed a reduction of 2.089 ㎍ of ascorbic acid. In the meantime, cell experiments showed cytotoxicity and anti-inflammatory functions against inflammation induced by LPS. In cytotoxicity experiments, Sargassum patens extracts showed a cell survival rate of more than 80% at all concentrations, and an inflammatory inhibition of 30.64±0.23% at a concentration of 100 ㎍/mL. These results indicate that Sargassum patens extract is available as an anti-inflammatory cosmetic material.
Keywords
Sargassum patens; Algae; Antioxidant; Anti-inflammation; Cosmetics;
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