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http://dx.doi.org/10.22156/CS4SMB.2020.10.05.232

Anti-aging & Skin Hydration Effects of Spore oil Extracted from Ganoderma lucidum  

Song, Hwan (Department of Beauty Design, Chodang University)
Kim, Myun Soo (Intercare R&D Center)
Publication Information
Journal of Convergence for Information Technology / v.10, no.5, 2020 , pp. 232-238 More about this Journal
Abstract
This study evaluated the anti-aging activity with antioxidant, anti-inflammatory and moisture activity of Ganoderma lucidum spore oil(GLS). GLS increased DPPH radical scavenging activity in a dose-dependent manners. Anti-inflammatory assay measured the inhibitory effect of GLS on NO, TNF-α and IL-6 production in LPS-stimulated RAW264.7 cells. As a result GLS inhibited NO and pro-inflammatory cytokine, TNF-α, IL-6 production. Also using human fibroblast cell to the procollagen production analysis and COL1A1 mRNA expression level analysis for defining, and for AQP-3 mRNA expression level analysis, used human keratinocyte cell. GLS increased procollagen production and COL1A1, AQP-3 mRNA expression. Our results suggest that the GLS have potential anti-inflammatory and wrinkle improves, skin moisture effect.
Keywords
Aquaporin 3; Ganoderma lucidum; Spore oil; Anti-inflammatory; Anti-aging;
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