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Histological Study on the Activated Carbon in the Rat Liver with Toxicated by Lead  

Chung, Min-Ju (Dept. of Biology, College of Natural Science, Chosun University)
Roh, Young-Bok (Dept. of Biology, College of Natural Science, Chosun University)
Publication Information
Applied Microscopy / v.32, no.2, 2002 , pp. 149-156 More about this Journal
Abstract
For investigation of the activated carbon in the rat liver toxicated by lead. Aniamls used $7{\sim}8$ weeks to Sparague-Dewley rat (150 g). The lead acetate (500 ppm) were injected and activated carbon (40 mg/kg) were treated orally for four and eight weeks, respectivelly, and observed by the electron microscope. The group with only lead for 4 weeks, The mitochondria and rough endoplasmic reticulum (rER) were extended and ribosomes dropped from the rER. The group with lead-activated carbon for 4 weeks, The number of lysosomes increased. The shapes of nucleus and rough endoplasmic reticulum observed almost similar with nomally. The group with only lead for 8 weeks, The mitochondria and rough endoplasmic reticulum (rER) were more extended. The group with lead-activated carbon for 8 weeks, the nucleus and rough endoplasmic reticulum was observed nomally.
Keywords
Activated carbon; Lead acetate; Liver; Rat;
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