Browse > Article
http://dx.doi.org/10.5229/JKES.2008.11.2.105

Electrochemical Characteristics of CNT/TiO2 Nanocomposites Electrodes for Cancer Cell Sensor  

Kim, Han-Joo (Department of Industrial Chemical Engineering, Chungbuk University)
You, Sun-Kyung (Department of Industrial Chemical Engineering, Chungbuk University)
Oh, Mi-Hyun (Department of Industrial Chemical Engineering, Chungbuk University)
Shen, Qin (State Key Laboratory of Bioelectronics, Southeast University)
Wang, Xuemei (State Key Laboratory of Bioelectronics, Southeast University)
Park, Soo-Gil (Department of Industrial Chemical Engineering, Chungbuk University)
Publication Information
Journal of the Korean Electrochemical Society / v.11, no.2, 2008 , pp. 105-108 More about this Journal
Abstract
In the recent years, increasing interests are being focused on the rational functionalization of the CNTs by some creative methods. However, the considerable toxicity of CNT is still a controversialissue and limits its biological application. To improve the biocompatibility of CNT, in this work we prepared CNT-$TiO_2$ nanocomposites with CNT and organic titanium precursors. Our observations demonstratethat the modified interface could accelerate the heterogeneous electron transfer rates and thusenhance the relevant detection sensitivity, suggesting its potential application as the new strategy for the development of the biocompatible and multi-signal responsive biosensors for the early diagnosis of cancers.
Keywords
CNT-; Electrochemistry; Cancer cell; Bioanalysis;
Citations & Related Records
연도 인용수 순위
  • Reference
1 B. M. Miller, E. Pujads, and E. Gocke,"Evaluation of the micronucleus test in vitro using Chinese hamster cells: results of four chemicals weakly positive in the in vivo micronucleus test", Environ. Mol. Mutagen., 26, 240 (1995)   DOI   ScienceOn
2 H. Chen, C. K. Heng, P. D. Puiu, X. D. Zhou, A. C. Lee, T. M. Lim, and S. N. Tan, "Detection of Saccharomyces cerevisiae immobilized on self -assembled monolayer (SAM) of alkanethiolate using electrochemical impedance spectroscopy", Anal. Chim. Acta, 554, 52 (2005)   DOI   ScienceOn
3 L. Ding, D. Du, J. Wu, and H. X. Ju, "A disposable impedance sensor for electrochemical study and monitoring of adhesion and proliferation of K562 leukaemia cells", Electrochem. Commun., 9, 953 (2007)   DOI   ScienceOn
4 V. Georgakilas, K. Kordatos, M. Prato, D. M. Guldi, M. Holzinger, and A. Hirsch, "Organic functionalization of carbon nanotubes" J. Am. Chem. Soc., 124, 760 (2002)   DOI   ScienceOn
5 B. R. Azamian, J. J. Davis, K. S. Coleman, C. B. Bagshaw, and M. L. H. Green, "Bioelectrochemical single-walled carbon nanotubes" J. Am. Chem. Soc., 124, 12664 (2002)   DOI   ScienceOn
6 Y. Wang, C. Y. Wang, and K. S. Chen,"Elucidating differences between carbon paper and carbon cloth in polymer electrolyte fuel cells", Electrochim. Acta, 52, 3965 (2007)   DOI   ScienceOn
7 R. H. Baughman, A. A. Zakhidov, and W. A. de Heer, "Carbon Nanotubes-the Route Toward Applications" Science, 297, 787 (2002)   DOI   ScienceOn
8 M. M. Gottesman and I. Pastan, "Biochemistry of multidrug resistance mediated by the multidrug transporter", Annu. Rev. Biochem., 62, 385 (1993)   DOI   ScienceOn
9 H. Li, B. Zhou, Y. Lin, L. Gu, W. Wang, K. A. S. Fernando, S. Kumar, L. F. Allard, and Y. Sun, "Selective in teractions of porphyrins with semiconducting single-walled carbon nanotubes", J. Am. Chem. Soc., 126, 1014 (2004)   DOI   ScienceOn
10 P. M. Ajayan, "Nanotubes from Carbon" Chem. Rev., 99, 1787 (1999)   DOI   ScienceOn
11 L. Dai, P. Soundarrajan, and T. Kim, "Sensors and sensor arrays based on conjugated polymers and carbon nanotubes" Pure Appl. Chem., 74, 1753 (2002)   DOI   ScienceOn
12 P. J. Britto, K. S. V. Santhanam, and P. M. Ajayan, "Carbon nanotube electrode for oxidation of dopamine" Bioelectrochem. Bioenerg, 41, 121 (1996)   DOI   ScienceOn
13 E. Pennisi, "Simple recipe yields fullerene tubules" Sci. News, 142, 36 (1992)
14 A. V. Ellis, K. Vijayamohanan, R. Goswami, N. Chakrapani, L. S. Ramanathan, P. M. Ajayan, and G. Ramanath, "Hydrophobic anchoring of monolayer-protected gold nanoclusters to carbon nanotubes", Nano Lett., 3, 279 (2003)   DOI   ScienceOn
15 R. B. Mathur, P. H. Maheshwari, T. L. Dhami, R. K. Sharma, and C. P. Sharma, "Processing of carbon composite paper as electrode for fuel cell", J. Power Sources, 161, 790 (2006)   DOI   ScienceOn
16 R. W. Tennant, B. H. Margolin, M. D. Shelby, E. Zeiger, J. K. Haseman, J. Spalding, W. Caspary, M. Resnick, S. Stasiewicz, B. Anderson, and R. Minor, "Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays", Science, 236, 933 (1987)   DOI
17 R. B. Mathur, P. H. Maheshwari, T. L. Dhami, and R. P. Tandon, "Characteristics of the carbon paper heat-treated to different temperatures and its influence on the performance of PEM fuel cell", Electrochim. Acta, 52, 4809 (2007)   DOI   ScienceOn
18 M. S. Saha, R. Y. Li, and X. L. Sun, Electrochem. Commun., 9, 2229 (2007)   DOI   ScienceOn
19 J. M. Haremza, M. A. Hahn, T. D. Krauss, S. Chen, and J. Calcines, "Attachment of single CdSe nanocrystals to individual single-walled carbon nanotubes", Nano Lett., 2, 1253 (2002)   DOI   ScienceOn
20 Y. P. Sun, K. Fu, Y. Lin, and W. J. Huang, "Functionalized carbon nanotubes : properties and applications" Acc. Chem. Res., 35, 1096 (2002)   DOI   ScienceOn
21 N. M. Dimitrijevic, Z. V. Saponjic, B. M. Rabatic, and T. Rajh, "Assembly and charge transfer in hybrid $TiO_2$ architectures using biotin-avidin as a connector", J. Am. Chem. Soc., 127, 1344 (2005)   DOI   ScienceOn