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http://dx.doi.org/10.6564/JKMRS.2017.21.4.131

HMQC vs HSQC for Small Molecules  

Kim, Eunhee (Protein Structure Group, Korea Basic Science Institute)
Cheong, Hae-Kap (Protein Structure Group, Korea Basic Science Institute)
Publication Information
Journal of the Korean Magnetic Resonance Society / v.21, no.4, 2017 , pp. 131-134 More about this Journal
Abstract
Proton detected Heteronuclear Multiple Quantum Coherence (HMQC) and Heteronuclear Single Quantum Coherence (HSQC) essentially provide the same information - correlation of the chemical shift of the proton to J-coupled hetero nuclei such as $^{13}C$ or $^{15}N$ nuclei. This paper is a practical note for the students who ask which one is better and which methods they use routinely. Artifact suppression using phase cycling and gradient pulses are discussed.
Keywords
HMQC; HSQC; Phase cycling; Gradient; Sensitivity;
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