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http://dx.doi.org/10.5660/KJWS.2010.30.4.421

Foliage Contact Herbicidal Activity of Dehydrocostus lactone Derived from Saussurea lappa  

Cho, Kwang-Min (Department of Bioenvironmental Chemistry and Research Center of Bioactive Materials, Chonbuk National University)
An, Xue-Hua (Zhejiang Academy of Agricultural Sciences)
Chon, Jae-Kwan (Department of Bioenvironmental Chemistry and Research Center of Bioactive Materials, Chonbuk National University)
Kim, Hyo-Sun (Department of Bioenvironmental Chemistry and Research Center of Bioactive Materials, Chonbuk National University)
Chun, Jae-Chul (Department of Bioenvironmental Chemistry and Research Center of Bioactive Materials, Chonbuk National University)
Publication Information
Korean Journal of Weed Science / v.30, no.4, 2010 , pp. 421-428 More about this Journal
Abstract
A foliage contact herbicidal substance was separated from ethyl ether fraction in n-hexane extract of Saussurea lappa roots and identified as dehydrocostus lactone [(3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[5,4-d]furan-2-one](DHCL). When DHCL at 4,000 ppm was foliage-applied to two grasses and two broadleaf plants, greater than 85% necrotic injury was obtained from large crabgrass, maize and soybean, whereas only about 40% necrotic injury appeared in black nightshade, indicating that DHCL has no gross morphological selectivity, but shows difference in contact response among the plant species tested. Conductivity in incubation medium of the leaf disks treated with DHCL increased as the incubation time continued. Relatively low contact injury in black nightshade as compared with the other three plant species tested was attributed to decrease in absorption of DHCL due to relatively high amount of cuticle. DHCL did not require light in the herbicidal action and there were no inhibitory effects on seed germination and cell elongation. Acetyl-CoA carboxylase activity was inhibited by 30% and 58% at $100\;{\mu}M$ and $1000\;{\mu}M$ DHCL, respectively. These results suggested that the herbicidal action of DHCL was related with inhibition of fatty acid synthesis which in turn caused to weaken cell membrane integrity.
Keywords
dehydrocostus lactone; herbicidal activity; Saussurea lappa;
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Times Cited By KSCI : 7  (Citation Analysis)
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