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http://dx.doi.org/10.5012/jkcs.2017.61.6.352

The Effect of Wettability and Protein Adsorption of Contact Lens by Alginic Acid  

Ko, Na Young (Department of Optometry & Vision Science, Catholic University of Daegu)
Lee, Kyung Mun (Vision Science CO. LTD)
Lee, Hyun Mee (Department of Optometry & Vision Science, Catholic University of Daegu)
Publication Information
Journal of the Korean Chemical Society / v.61, no.6, 2017 , pp. 352-358 More about this Journal
Abstract
The addition of alginic acid, a natural polysaccharide, to improve the wettability and the reduction of protein adsorption of hydrogel contact lenses. Hydrogel contact lenses were manufactured with various monomers such as 2-methacryloyloxyethyl phosphorylcholine (MPC) and NVP (N-Vinyl-2-pyrrolidone). Alginic acid was added by by the initial mixing method and the interpenetrating polymer networks(IPN) method. Properties of contact lens such as contact angle, oxygen permeability, and protein adsorption amount were evaluated. The oxygen permeability and wettability of the IPN-treated alginate samples were higher than those of the samples that were not treated with IPN. The physical properties were improved as the concentration of IPN-treated alginic acid increased. Protein adsorption decreased by the addition of alginic acid and further decreased with IPN. In particular, contact lenses containing MPC and NVP significantly decreased protein adsorption. Therefore, the effect of alginate on the functional improvement of contact lens was confirmed.
Keywords
Alginic acid; Wettability; Oxygen permeability; Protein adsorption; IPN;
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