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http://dx.doi.org/10.5012/jkcs.2015.59.2.136

Synthesis and Characterization of CdSe/CdS/N-Acetyl-L-Cysteine/Quercetin Nano-Composites and Their Antibacterial Performance  

Wang, Kunjie (College of Petrochemical Technology, Lanzhou University of Technology)
Li, Mingliang (College of Petrochemical Technology, Lanzhou University of Technology)
Li, Hongxia (College of Petrochemical Technology, Lanzhou University of Technology)
Guan, Feng (College of Petrochemical Technology, Lanzhou University of Technology)
Zhang, Deyi (College of Petrochemical Technology, Lanzhou University of Technology)
Feng, Huixia (College of Petrochemical Technology, Lanzhou University of Technology)
Fan, Haiyan (Chemistry Department, Nazarbayev University)
Publication Information
Journal of the Korean Chemical Society / v.59, no.2, 2015 , pp. 136-141 More about this Journal
Abstract
We have discovered that quercetin, once coated on the CdSe and CdSe-CdS quantum dots (QDs), becoming highly water soluble. In the present work, we have successfully synthesized CdSe/CdS/N-Acetyl-L-Cysteine(NAC)/Quercetin nano-composites in the aqueous solution. The products were characterized using UV-vis spectroscopy, X-ray powder diffraction, fluorescence spectroscopy, and Fourier transform infrared spectroscopy. The transmission electron microscopy (TEM) tests indicated that our nano-composite products are highly stable with homogeneous particle size and great monodispersity. Quercetin coated nano-composite CdSe/CdS/NAC/Quercetin showed different fluorescence behavior from that of CdSe/CdS/NAC. Most amazingly, the synthesized CdSe/CdS/NAC/Quercetin nano-composite exhibits strong antibacterial activity. The combination of the strong fluorescence and its antibacterial activity makes the quercetin modified quantum dots as a potential candidate for cancer targeted therapy and other cancer treatments.
Keywords
Quantum dots; Core-shell; CdSe/CdS; Quercetin;
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