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http://dx.doi.org/10.5012/jkcs.2014.58.1.33

Synthesis and in Vitro Antimicrobial Evaluation of Benzothiazole Incorporated Thiazolidin-4-ones Derivatives  

Agarwal, Shikha (Department of Chemistry, Mohan Lal Sukhadia University)
Agarwal, Dinesh Kumar (Department of Pharmacology, Arya College of Pharmacy)
Gautam, Naveen (Department of Chemistry, L.B.S. Govt. P.G. College)
Agarwal, Kshamta (Department of Chemistry, University of Rajasthan)
Gautam, Dinesh Chandra (Department of Chemistry, University of Rajasthan)
Publication Information
Journal of the Korean Chemical Society / v.58, no.1, 2014 , pp. 33-38 More about this Journal
Abstract
In the course of work on new pharmacologically active antimicrobial agents, we have reported the synthesis of a new class of structurally novel derivatives, incorporating two bioactive structures, a benzothiazole and thiazolidin-4-one, to yield a class of compounds having interesting antimicrobial properties. The antimicrobial properties of the synthesized compounds were investigated against bacteria (Staphylococcus aureus and Escherchia coli) and fungi (Candida albicans and Aspergillus niger) using serial plate dilution method. The structure of the synthesized compounds have been established by elemental analysis and spectroscopic data.
Keywords
Benzothiazole; Thiazolidin-4-ones; N-(5,7-dimethylbenzo[d]thiazol-2-yl)hydrazine carboxamide; Antimicrobial activity;
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