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http://dx.doi.org/10.5012/jkcs.2013.57.5.599

Solvent-Free Synthesis of Some1-Acetyl Pyrazoles  

Thirunarayanan, Ganesamoorthy (Department of Chemistry, Annamalai University)
Sekar, Krishnamoorthy Guna (Department of Chemistry, National College)
Publication Information
Journal of the Korean Chemical Society / v.57, no.5, 2013 , pp. 599-605 More about this Journal
Abstract
Some N-acetyl pyrazoles including 1-(3-(3,4-dichlorophenyl)-5-(substituted phenyl)-4,5-dihydro-$^1H$-pyrazole- 1-yl) ethanones have been synthesised by solvent free cyclization cum acetylation of chalcones like substituted styryl 3,4- dichlorophenyl ketones using hydrazine hydrate and acetic anhydride in presence of catalytic amount of fly-ash: $H_2SO_4$ catalyst. The yield of these N-acetyl pyrazole derivatives are more than 75%. The synthesised N-acetyl pyrazoline derivatives were characterized by their physical constants and spectral data.
Keywords
Solvent-free cyclization cum acetylation; N-acetyl pyrazoles; IR; NMR spectra;
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