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http://dx.doi.org/10.5012/jkcs.2013.57.4.476

One Pot Synthesis of Bioactive Novel Cyanopyridones  

Khokhani, Kamlesh (Department of Chemistry, M M Science College)
Khatri, Taslimahemad (Department of Chemistry, KSKV Kachchh University)
Patel, Praful (Department of Chemistry, M M Science College)
Publication Information
Journal of the Korean Chemical Society / v.57, no.4, 2013 , pp. 476-482 More about this Journal
Abstract
Cyanopyridone was prepared by the condensation of cyanoacetamide, substituted arylaldehydes and malononitrile in presence of pipyridine. The structure of the synthesized compound CP 1-20 was assigned on the basis of elemental analysis, IR, $^1H$-NMR and mass spectroscopy. These compounds were also screened for antimicrobial activity. The Minimum Inhibitory Concentration (MIC) of all the synthesized compounds was compared with standard drugs.
Keywords
Cyanopyrimidones; Cyanoacetamide; Antimicrobial activity; Malononitrile; Pipyridine;
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