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http://dx.doi.org/10.5012/jkcs.2013.57.2.260

ZrOCl2·8H2O as an Efficient Catalyst for the Pseudo Four-Component Synthesis of Benzopyranopyrimidines  

Tavakoli, Hamid Reza (Department of Chemistry, Shahid Beheshti University)
Moosavi, Sayed Mojtaba (Department of Chemistry, Imam Hossein University)
Bazgir, Ayoob (Department of Chemistry, Shahid Beheshti University)
Publication Information
Journal of the Korean Chemical Society / v.57, no.2, 2013 , pp. 260-263 More about this Journal
Abstract
An efficient and environmentally benign protocol for the pseudo four-component synthesis of benzopyranopyrimidines via condensation of salicylic aldehydes, malononitrile and various amines catalyzed by $ZrOCl_2{\cdot}8H_2O$ as an inexpensive and eco-friendly catalyst with high catalytic activity under solvent-free conditions is reported. This protocol provides a new and improved method for obtaining benzopyranopyrimidines in terms of good yields, simple experimental procedure and short reaction time.
Keywords
Solvent-free; Malononitrile; Benzopyranopyrimidine; Salicylaldehyde;
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